Risk Factors of Cognitive Impairment and Brief Cognitive Tests to Predict Cognitive Performance Determined by a Formal Neuropsychological Evaluation of Primary Health Care Patients

Journal of the American Medical Directors Association
Muhammad Amin ShaikYanHong Dong

Abstract

Case finding for cognitive impairment (CI) is recommended for all persons older than 70 years. The present study identified additional risk factors of CI so as to operationalize a composite total risk score (TRS) for case finding. We then examined the additive effect of the TRS and brief cognitive tests to improve the diagnosis of CI. The study was conducted in 2 primary health care centers in Singapore. A total of 1082 individuals (≥60 years old) were assessed for sociodemographic risk factors and their informants were administered the AD8; 309 individuals who agreed for further cognitive assessments completed the Mini-mental state examination (MMSE) and Montreal Cognitive Assessment (MoCA), and a neuropsychological battery at a research center. Primary health care medical records were accessed for data on vascular risk factors. Of the 309 individuals who underwent neuropsychological evaluation, 4 were excluded due to missing medical data; 167 (54.8%) individuals had CI and 138 (45.2%) had No Cognitive Impairment (NCI). The β coefficients were standardized to calculate risk scores. CI was significantly predicted by age >70 years (odds ratio [OR] 5.99; score = 3), diabetes (OR 3.36; score = 2), stroke (OR 2.70; score = 1), fema...Continue Reading

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Citations

Jun 28, 2016·Journal of the American Medical Directors Association·Muhammad Amin ShaikYanHong Dong
Aug 1, 2016·Journal of the American Medical Directors Association·John E Morley, Susan A Farr
Sep 4, 2016·Journal of the American Medical Directors Association·John E Morley
Oct 27, 2016·Journal of the American Medical Directors Association·Anthony LicciniJohn E Morley
Sep 6, 2018·Applied Neuropsychology. Adult·Isabel Pavão MartinsPaulo Marques
Apr 6, 2019·Journal of Molecular Neuroscience : MN·Xiaojun ZhangJing Zhou
Jul 10, 2019·Dementia & Neuropsychologia·Lucas N C PelegriniFrancisco A C Vale
Nov 16, 2018·Frontiers in Neurology·Young-Kook KimJuhyun Song
Mar 28, 2018·The Journal of Nutrition, Health & Aging·A M SanfordA McKee
May 5, 2021·Nutrition Reviews·Pablo Arrona CardozaElisa Morales Marroquin

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