PMID: 19140385Jan 15, 2009Paper

Risk factors of hearing impairment in premature infants

Przegla̧d lekarski
Tomasz Tomasik

Abstract

The incidence of sensorineural hearing impairment among premature infants--survivors of intensive care--is high. The purpose of this study was to identify the risk factors of hearing impairment in this group of children. Prospective cohort study (2.10.96-17.11.02). A total of 218 premature infants with birth weight 520-3000 g (Me-1300 g) and gestational age 22-36 weeks (Me-30) were tested by ABR and divided into 2 groups: with hearing impairment n = 18 and control n = 200. The logistic regression analysis was performed to identify the independent risk factors of hearing impairment. Significant risk factors of hearing impairment were: gestation age (OR: 0.7; 95% CI: 0.6-0.97), hyperbilirubinemia qualified for exchange transfusion (OR: 13; 95% CI: 2.9-64), severe general condition and prolonged use of katecholamines > 8 days (OR: 18; 95% CI: 3.6-96), treatment with amikacin > 15 days (OR: 8; 95% CI: 1.6-43), hypoglycaemia < or = 2.46mmol/l (OR: 6; 95% CI: 1.2-23). Mechanical ventilation > 14 days was an additional risk factor associated with gestational age (OR: 8; 95% CI: 1.1-65). The model evaluated by logistic regression could predict 13 out of 18 hearing impairment cases (72%). The independent risk factors of hearing impairme...Continue Reading

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