Risk Factors of Multidrug-Resistant Bacteria in Lower Respiratory Tract Infections: A Systematic Review and Meta-Analysis

The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Médicale
Gang ChenBangjiang Fang

Abstract

Multidrug-resistant (MDR) bacteria are the main cause of lower respiratory tract infections (LRTIs) with high mortality. The purpose of this study is to identify the risk factors associated with MDR by performing a systematic review and meta-analysis. PubMed, EMBASE (via Ovid), and Cochrane Library were systematically searched for studies on the risk factors for MDR bacteria in LRTIs as of November 30, 2019. Literature screening, data abstraction, and quality assessment of the eligible studies were performed independently by two researchers. A total of 3,607 articles were retrieved, of which 21 articles representing 20 cohort studies published in English were included after title/abstract and full-text screening. Among the 21 articles involving 7,650 patients and 1,360 MDR organisms, ten reported the risk factors for MDR Gram-positive bacteria (GPB) and Gram-negative bacteria (GNB), ten for MDR GNB, and one for MDR GPB. The meta-analysis results suggested that prior antibiotic treatment, inappropriate antibiotic therapy, chronic lung disease, chronic liver disease and cerebral disease, prior MDR and PA infection/colonization, recent hospitalization, longer hospitalization stay, endotracheal tracheostomy and mechanical ventilati...Continue Reading

References

Feb 9, 2005·American Journal of Respiratory and Critical Care Medicine·UNKNOWN American Thoracic Society, UNKNOWN Infectious Diseases Society of America
Mar 22, 2006·Annals of Internal Medicine·Jill A HaydenClaire Bombardier
Jan 19, 2008·American Journal of Respiratory and Critical Care Medicine·Timothy F MurphySanjay Sethi
Nov 8, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Laura Martínez-SolanoJose L Martinez
Nov 19, 2008·Critical Care : the Official Journal of the Critical Care Forum·Pieter O DepuydtDominique D Benoit
Jul 29, 2011·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A-P MagiorakosD L Monnet
Mar 26, 2013·American Journal of Infection Control·Yu-long ZhengJian-hui Chen
Jul 17, 2013·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Renato SeligmanElyara Fiorin Pacheco
Mar 19, 2014·American Journal of Infection Control·Rudy TedjaDavid van Duin
Jun 25, 2014·Antimicrobial Agents and Chemotherapy·Alan E GrossAndre C Kalil
Jun 5, 2015·Statistics in Medicine·Andrea GonnermannArmin Koch
Sep 12, 2015·Annals of the American Thoracic Society·Marcus RuoppEphraim L Tsalik
Jul 16, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Andre C KalilJan L Brozek
Jul 23, 2016·International Journal of Antimicrobial Agents·Sheng-Feng HuangYing-Chi Lin
Oct 27, 2016·Current Opinion in Infectious Diseases·Matteo BassettiDavide Pecori
Oct 19, 2016·Biometrical Journal. Biometrische Zeitschrift·Tim FriedeBeat Neuenschwander
Nov 21, 2016·The Journal of Infection·Laia Fernández-BaratAntoni Torres
Jun 2, 2017·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Richard E NelsonMatthew H Samore
Jul 19, 2017·Diagnostic Microbiology and Infectious Disease·Trang D TrinhMichael J Rybak
Jul 28, 2017·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Pin LiuJingfu Qiu
Sep 14, 2017·Proceedings of the National Academy of Sciences of the United States of America·Joyce WangEvan S Snitkin
Feb 2, 2018·International Journal of Chronic Obstructive Pulmonary Disease·Yong-Hua GaoGuo-Jun Zhang
Mar 27, 2018·International Journal of Nursing Practice·Hui Ang, Xuan Sun
Apr 18, 2018·The Journal of Trauma and Acute Care Surgery·Richard H LewisLouis J Magnotti
Jul 22, 2018·The Journal of International Medical Research·Ying LuanZhongying Bao

❮ Previous
Next ❯

Software Mentioned

Excel
Ovid
R
Stata
Quality in Prognosis Studies ( QUIPS )
PRISMA

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.