Risk factors of nasal carriage of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus among health care staff in a teaching hospital in central Saudi Arabia

Saudi Medical Journal
Ohoud S Al-HumaidanRaid A Al-Akeel

Abstract

To investigate possible risk factors of Staphylococcus aureus (S. aureus) and methicillin-resistant S. aureus (MRSA) nasal carriage associated with various health troubles among healthcare workers (HCWs) at King Khalid University Hospital (KKUH). This prospective study was conducted between May 2012 and January 2013 in KKUH, Riyadh, Saudi Arabia. A total of 200 nasal swabs were collected from HCWs. Identification was carried out based on morphology, Gram stain, catalase and coagulase test, Staphaurex PlusH test, chromogenic medium, oxacillin, and cefoxitin test using disc diffusion method. Characterization was carried out using disk diffusion method and E-test. Polymerase chain reaction was carried out to confirm using GeneXpert® Dx System (Cepheid) to detect mecA gene. Among the 200 isolates, 80 (40%) were S. aureus carriers, and 36 (18%) of all HCWs were identified as MRSA carriers. There was a significant difference of S. aureus according to gender with male carriers (p=0.012), occupation particularly among nurses (p=0.006), and duration of working years in the hospital among 4-6 years group (p=0.002). Moreover, none of the risk factors assessed were significantly associated with the carriage rate of MRSA (p greater than 0.0...Continue Reading

Citations

Mar 25, 2014·BMC Infectious Diseases·Shamshul AnsariMoti Lal Chapagain
Apr 24, 2016·Journal of Infection and Public Health·Hanan H BalkhyUNKNOWN at the workshop
Apr 19, 2017·Journal of Global Antimicrobial Resistance·Nawfal R HusseinTayyaba Ijaz
Mar 22, 2019·Annals of Clinical Microbiology and Antimicrobials·Mary Dias, Juveyriya Saleem
Jun 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Basma NajarLuisa Pistelli
May 27, 2021·International Journal of Microbiology·Arwa Mohammed OthmanHuda Zaid Al-Shami

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Methods Mentioned

BETA
Assay
PCR

Software Mentioned

Statistical Package for Social Sciences

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