PMID: 16512176Mar 4, 2006Paper

Risk factors of pulmonary tuberculosis in children with chronic nonspecific lung diseases

Problemy tuberkuleza i bolezneĭ legkikh
A I Mokhnachevskaia, V A Aksenova

Abstract

Data on 2362 children and adolescents with chronic nonspecific lung diseases (CNLD) registered in the tuberculosis dispensaries of 5 areas of the Republic of Sakha (Yakutia) served as a clinical material for the study. Analysis of the outpatient cards of 234 children and adolescents followed up in the dispensaries for tuberculosis revealed a nonspecific bronchopulmonary disease preceding tuberculosis in 110 (47%) patients. Before falling ill with tuberculosis, 16 (15%) children had suffered from frequent colds, 41 (37%) children were found to have as many as 2-3 acute infections a year. Out of them, 12 (11%), 33 (30%), and 8 (7%) had prior pneumonia, acute bronchitis, and chronic bronchitis, respectively. This study has indicated that the late detection of a specific process in general health care facilities leads to complicated tuberculosis. This makes its treatment difficult and promotes the development of pronounced residual changes in the lung. A differential approach to examining a child or an adolescent, allowing for the aggravating factors of development of tuberculosis, and determination of the risk may significantly increase the number of patients with comorbidity, detected in due time.

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