Abstract
Stenotrophomonas maltophilia, is a nonfermentative, aerobic, Gram-negative bacilli which is intrinsically resistance to several antibiotics. Treatment options for this bacteria are quite different from the other Gram-negative bacilli, which can represent a therapeutic challenge. To initiate appropriate empiric treatment and to reduce mortality, differentiation of S. maltophilia from other Gram-negative bacteria is critically important. The aim of this study is to distinguish the risk factors of S. maltophilia blood stream infections (BSI) from other Gram-negative BSI. This was a retrospective, case-control study. Patients with S. maltophilia BSI were selected as cases and patients with non-S. maltophilia Gram-negative BSI were selected as controls. Demographic and clinical characteristics of patients were recorded. Forty-eight cases with S. maltophilia BSI and 144 controls were enrolled in the study. Risk factors for S. maltophilia BSI compared with the control group includes prior use of antibiotics, especially carbapenem, pediatric intensive care unit stay, mechanical ventilator use, indwelling catheters and duration of hospitalization. Breakthrough infection by S. maltophilia can occur in severely ill patients being treated ...Continue Reading
References
Jun 1, 1988·American Journal of Infection Control·J S GarnerJ M Hughes
Mar 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·R R MuderJ M Steckelberg
May 9, 2002·Medicine·Maria Dolores del ToroUNKNOWN Grupo Andaluz para el Estudio de las Enfermedades Infecciosas
May 29, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Esin SenolDavid R Snydman
May 3, 2003·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Anucha ApisarnthanarakLouis B Polish
Jun 27, 2006·Scandinavian Journal of Infectious Diseases·Gokhan MetanOmrum Uzun
May 29, 2007·The Pediatric Infectious Disease Journal·Jessica KagenSamir S Shah
Jun 10, 2008·American Journal of Infection Control·Teresa C HoranMargaret A Dudeck
Feb 19, 2009·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M E FalagasG Dimopoulos
Apr 28, 2009·The Lancet Infectious Diseases·W John LooneyKathrin Mühlemann
Feb 24, 2010·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·H AraokaA Yoneyama
Jan 24, 2013·Journal of Korean Medical Science·Hae-Sun ChungYunsop Chong
Oct 23, 2013·Antimicrobial Agents and Chemotherapy·Yu Lin WangJohn Papadopoulos
Aug 2, 2014·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Ching-Hsun WangKuo-Ming Yeh
Nov 7, 2014·PloS One·Go HottaSatoshi Ichiyama
Jul 4, 2015·Pediatrics International : Official Journal of the Japan Pediatric Society·Munehiro FuruichiIsao Miyairi
Aug 9, 2016·Medicine·Yong Duk JeonNam Su Ku
Jan 17, 2017·Internal Medicine·Hirotaka EbaraFumio Otsuka