Risk for All-cause and Traumatic Death in Head Trauma Subjects: A Prospective Population-based Case-control Follow-up Study

Annals of Surgery
Jussi PuljulaMatti Hillbom

Abstract

To investigate long-term mortality for subjects with acute head trauma. It is not known why long-term mortality after head trauma without traumatic brain injury is elevated. All subjects admitted to Oulu University Hospital emergency room in 1999 with an acute head trauma (n = 737) were followed up until February 2014 and compared with age and sex-matched general population controls (n = 2196). Dates and causes of death were obtained from the official Cause-of-Death Statistics. Cox proportional hazard regression models and Kaplan-Meier survival curves were used to identify predictors for alcohol-related, nonalcohol-related, and all-cause death. Alcohol-related deaths were more frequent among the subjects with head trauma (27.8%) than among the population controls (6.9%). Head trauma with or without traumatic brain injury (TBI) shortened mean life expectancy by 8.7 years and by as much as 13 years if only those without TBI were considered. The risk of alcohol-related death was 7-fold (hazard ratio 6.79; 95% confidence interval, 3.94-11.71) among subjects without TBI as compared with general population. Of all future deaths among these cases 17.1% were because of a new trauma, a significantly higher frequency (P < 0.005) than tha...Continue Reading

References

Aug 1, 1995·Annals of Emergency Medicine·S S DikmenN R Temkin
Apr 1, 1995·Archives of Physical Medicine and Rehabilitation·J D Corrigan
Jun 23, 2004·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Olli SavolaMatti Hillbom
May 5, 2005·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Olli SavolaMatti Hillbom
May 17, 2005·Journal of the International Neuropsychological Society : JINS·Rodney D VanderploegHeather G Belanger
Jun 15, 2006·Addiction·Guilherme BorgesVladimir Poznyak
Sep 20, 2007·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·A K Rose, T Duka
Feb 11, 2009·Journal of Neurotrauma·James M Bjork, Steven J Grant
Sep 9, 2009·Archives of Physical Medicine and Rehabilitation·Cynthia L Harrison-FelixDenise M Hart
Jan 28, 2010·Archives of Physical Medicine and Rehabilitation·Thomedi VenturaGale Whiteneck
Mar 9, 2011·Addiction·Joseph M Boden, David M Fergusson
Apr 3, 2013·The American Journal of Psychiatry·John D CorriganMary Jo Larson
Nov 19, 2013·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·K VaaramoM Hillbom
Dec 18, 2013·Psychopharmacology·Abigail K RosePaul Christiansen
Mar 14, 2014·Journal of Neurology, Neurosurgery, and Psychiatry·T M McMillanJ Wainman-Lefley
Aug 1, 2014·Frontiers in Psychiatry·Florent BernardinFrançois Paille

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.

© 2021 Meta ULC. All rights reserved