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Risk for lower intestinal perforations in patients with rheumatoid arthritis treated with tocilizumab in comparison to treatment with other biologic or conventional synthetic DMARDs

Annals of the Rheumatic Diseases

Mar 1, 2017

Anja StrangfeldJoachim Listing

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Abstract

To investigate the risk of developing lower intestinal perforations (LIPs) in patients with rheumatoid arthritis (RA) treated with tocilizumab (TCZ). In 13 310 patients with RA observed in the German biologics register Rheumatoid Arthritis: Observation of Biologic Therapy, 141 serious g...read more

Mentioned in this Paper

Abdomen
Abdomen, Acute
Antirheumatic Agents
Steroidal anti-inflammatory drugs
Rheumatoid Arthritis
Biological Products
Biological Response Modifier Therapy
C-reactive protein
Colon Structure (Body Structure)
Diverticulitis
12
2
2
77
Paper Details
References
  • References19
  • Citations16
12
  • References19
  • Citations16
12

Risk for lower intestinal perforations in patients with rheumatoid arthritis treated with tocilizumab in comparison to treatment with other biologic or conventional synthetic DMARDs

Annals of the Rheumatic Diseases

Mar 1, 2017

Anja StrangfeldJoachim Listing

PMID: 27405509

DOI: 10.1136/annrheumdis-2016-209773

Abstract

To investigate the risk of developing lower intestinal perforations (LIPs) in patients with rheumatoid arthritis (RA) treated with tocilizumab (TCZ). In 13 310 patients with RA observed in the German biologics register Rheumatoid Arthritis: Observation of Biologic Therapy, 141 serious g...read more

Mentioned in this Paper

Abdomen
Abdomen, Acute
Antirheumatic Agents
Steroidal anti-inflammatory drugs
Rheumatoid Arthritis
12
2
2
77

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Paper Details
References
  • References19
  • Citations16
12
  • References19
  • Citations16
12

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