PMID: 9161469Jan 1, 1997Paper

Risk of diarrhoea, Clostridium difficile and cefotaxime in the elderly

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
J M Starr, M Impallomeni

Abstract

Clostridium difficile diarrhoea is an increasingly important nosocomial infection. Clostridium difficile infection is associated with antibiotic use. The elderly are at greatest risk. We reported an outbreak associated with the use of cefotaxime, a third-generation cephalosporin. We review the extent of this association, putative causal mechanisms and suggest an integrated approach to the control of C difficile infection which focuses on both limiting environmental contamination and reducing patient susceptibility. Future developments are also considered, especially the potential for vaccination.

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Citations

Aug 17, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kathleen M MullaneSherwood L Gorbach
Oct 15, 2013·Journal of Gastroenterology and Hepatology·Lawrence R SchillerJoseph H Sellin
May 16, 2008·Journal of Medical Microbiology·Cécile DenèveClaire Janoir
Oct 10, 2001·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·J M Starr, A Campbell
Feb 8, 2003·Der Urologe. Ausg. A·C GrebT Kälble

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