Risk of emergency medical treatment following consumption of cannabis or synthetic cannabinoids in a large global sample

Journal of Psychopharmacology
Adam WinstockJon Waldron

Abstract

Synthetic cannabinoids (SCs) have become increasingly popular in recent years. Diverse in chemical structure, many have been subjected to legislative regulation, but their availability and use persists. Often marketed to reflect their similar effects to cannabis, their use has been associated with a range of negative health effects. We sought to determine the relative risk of seeking emergency medical treatment (EMT) following use of SCs and natural cannabis. We utilized an anonymous online survey of drug use, obtaining data from 22,289 respondents. We calculated the relative risk of seeking EMT between the two substances using an estimate for days used in the past year. Thirty-seven cannabis users (0.2%) and 21 SC users (1.0%) had sought EMT during the past year following use. The relative risk associated with the use of SCs was 30 (95% CI 17.5-51.2) times higher than that associated with cannabis. Significantly more symptoms (p=0.03) were reported by respondents seeking treatment for SCs than for cannabis. Whilst these findings must be treated with caution, SCs potentially pose a greater risk to users' health than natural forms of cannabis. Regulation is unlikely to remove SCs from the market, so well-informed user-focused he...Continue Reading

References

Jan 30, 2003·Journal of Medical Internet Research·Gunther Eysenbach, Jeremy Wyatt
Dec 23, 2003·Drug and Alcohol Dependence·Libby ToppLouisa Degenhardt
Jul 16, 2010·Addiction·Peter G Miller, Anders L Sønderlund
Jan 6, 2011·British Journal of Clinical Pharmacology·Emilie JouanjusMaryse Lapeyre-Mestre
Feb 15, 2011·Drug and Alcohol Dependence·Susanna Every-Palmer
Apr 13, 2011·The International Journal on Drug Policy·Paul I DarganDavid M Wood
May 14, 2011·Psychosomatics·Dawn M Benford, Jason P Caplan
May 20, 2011·Addiction·Adam WinstockJohn Marsden
Oct 19, 2011·Frontiers in Behavioral Neuroscience·Liana Fattore, Walter Fratta
Dec 14, 2011·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Aaron B Schneir, Todd Baumbacher
Mar 16, 2012·BJU International·Adam R WinstockAngela M Cottrell
Mar 16, 2012·Journal of Analytical Toxicology·Kevin G ShanksAndrea R Terrell
Mar 21, 2012·Pediatrics·Joanna CohenMohsen Saidinejad
May 9, 2012·Progress in Neuro-psychopharmacology & Biological Psychiatry·Kathryn A SeelyLiana Fattore
Sep 20, 2012·The Journal of Emergency Medicine·Carson R Harris, Ashley Brown
Dec 18, 2012·Clinical Journal of the American Society of Nephrology : CJASN·Gautam Kantilal BhanushaliDenyse Thornley-Brown
Jan 22, 2013·Journal of Chromatography. a·Donata FavrettoFranco Tagliaro
Jul 10, 2013·Psychopharmacology·Max SpadernaDeepak Cyril D'Souza

❮ Previous
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Citations

Nov 17, 2015·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Robert J TaitSimon Lenton
Dec 24, 2015·Journal of Forensic and Legal Medicine·Nazim Ercument BeyhunHuseyin Cetin Ketenci
Apr 12, 2016·The American Journal of Drug and Alcohol Abuse·Joseph J Palamar, Monica J Barratt
May 11, 2016·Drug Testing and Analysis·Anca FrinculescuBram Miserez
May 24, 2016·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Alice SeywrightRichard Stevenson
Oct 8, 2016·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Robin M MurrayMarta Di Forti
Sep 10, 2016·Journal of Clinical Pharmacology·C Michael White
Jun 22, 2017·Neuropharmacology·R M MurrayD C D'Souza
Aug 30, 2017·European Addiction Research·Stella WelterHelge H O Müller
Aug 17, 2017·Journal of Psychoactive Drugs·Kirsten Elin SmithKevin Pangburn
Sep 20, 2017·Substance Abuse : Research and Treatment·Monica J BarrattAdam R Winstock
Jan 2, 2020·Journal of Neural Transmission·Phil Skolnick, Roger Crystal
Apr 10, 2020·Therapeutic Advances in Drug Safety·Jules C HancoxGraeme Henderson
Apr 20, 2017·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Rachelle AbouchedidPaul I Dargan
Apr 21, 2017·British Journal of Pharmacology·L-S Camilla d'AngeloBarbara J Sahakian
May 8, 2018·Journal of Psychopharmacology·Balázs SzigetiLarissa J Maier
Sep 8, 2017·Frontiers in Psychiatry·Aviv M WeinsteinEdythe D London
Feb 23, 2019·Journal of Psychopharmacology·Hina AkramH Valerie Curran
Jun 6, 2016·The American Journal of Case Reports·Thiru ChinnaduraiRaji Ayinla
Oct 29, 2020·European Journal of Public Health·Bobby P SmythWalter Cullen
Jan 9, 2021·Therapeutic Advances in Psychopharmacology·Abu ShafiDerek K Tracy
Feb 12, 2021·International Journal of Emergency Medicine·Kevin M Takakuwa, Raquel M Schears
Jul 28, 2021·Journal of Cannabis Research·Melissa A JacksonAdrian J Dunlop
Aug 4, 2021·The International Journal on Drug Policy·Shane DarkeJulia Lappin
Dec 5, 2019·ACS Chemical Neuroscience·Adam Worob, Cody Wenthur
Jul 10, 2019·Pediatrics·Sarah Ann R AndersonUNKNOWN ToxIC Investigators
Sep 13, 2017·Pediatrics·Joseph J PalamarSilvia S Martins

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