PMID: 8585637Oct 1, 1995Paper

Risk of hepatitis C seroconversion after occupational exposures in health care workers. Italian Study Group on Occupational Risk of HIV and Other Bloodborne Infections

American Journal of Infection Control
V PuroG Ippolito

Abstract

To determine the incidence of hepatitis C virus (HCV) seroconversion, health care workers reporting an occupational exposure with blood or other risk-prone body materials from a patient known to be seropositive for HCV antibody were enrolled. HCV seroconversion within 6 months of a reported exposure was assessed by second-generation enzyme immunoassay and immunoblot assay. From January 1992 through December 1993, 331 (51%) hollow-bore needlesticks, 105 (16.5%) suture needle or sharp object injuries, 85 (13%) mucous membrane contaminations, and 125 (19.5%) skin contaminations were reported. Four HCV seroconversions were observed after hollow-bore needlesticks (1.2%; 95% CI 0.3% to 3.0%); no seroconversions occurred after other routes of exposure. Blood-filled needlesticks and source patient coinfection with HIV appeared to be associated with a higher risk of seroconversion. The risk of HCV seroconversion after occupational exposure appears to be low but is not negligible. Aggressive implementation of universal precautions is important for preventing risk-prone exposure, but safer devices are also needed.

Associated Clinical Trials

Citations

Mar 14, 2000·Reviews in Medical Virology·J Heptonstall
Apr 21, 1999·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·A M Ho, E Ling
Jul 10, 2007·Current Infectious Disease Reports·Arthur Y Kim, Georg M Lauer
Dec 4, 2003·American Journal of Infection Control·Salih HosogluIsmail Hamdi Kara
Nov 7, 2000·Current Surgery·S S Florman, R L Nichols
May 2, 2001·American Journal of Preventive Medicine·G RischitelliT Guidotti
Sep 5, 2002·Journal of Clinical Anesthesia·Bryan A LiangBruce Cullen
Feb 13, 2002·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·A MeleG Traversa
Oct 31, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Bruce R Bacon
Oct 31, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Miriam J Alter
Dec 19, 2002·Journal of Clinical Gastroenterology·Tommy YenAijaz Ahmed
May 4, 2006·Journal of Pediatric Orthopedics·Ibrahim Al-HabdanMir Sadat-Ali
Aug 6, 2003·Plastic and Reconstructive Surgery·Robert A YohoAndrea T Cruz
Oct 1, 2009·Journal of Gastroenterology and Hepatology·Kate DolanWilliam Rawlinson
Jul 25, 2000·Clinical Microbiology Reviews·E M BeltramiM E Chamberland
Jul 15, 2003·Clinical Microbiology Reviews·David K Henderson
Sep 27, 2008·Infectious Diseases in Obstetrics and Gynecology·Bernard Gonik
Jul 26, 2011·Gastroenterology Research and Practice·Olive ObienuOlufunmilayo A Lesi
Oct 2, 2013·Nature Reviews. Gastroenterology & Hepatology·Mark Thursz, Arnaud Fontanet
Aug 14, 2008·International Journal of Prisoner Health·Sarah Larney, Kate Dolan
Apr 9, 2001·American Journal of Public Health·T C PorcoD R Bangsberg
Sep 1, 2007·Renal Failure·I GriveasD Papadopoulou
Jun 23, 2012·Journal of the Chinese Medical Association : JCMA·Chia-Chun HungTsuo-Hung Lan
Mar 3, 2009·Medicina clínica·Víctor Manuel Solano Bernad
Dec 25, 2007·Annales Françaises D'anesthèsie Et De Rèanimation·F Mérat, S Mérat
Oct 16, 2007·American Journal of Infection Control·Karen SlaterMary-Louise McLaws
Dec 13, 2006·American Journal of Infection Control·Donna HaiduvenJune Fisher
May 1, 2004·Journal of Viral Hepatitis·M KewUNKNOWN Viral Hepatitis Prevention Board
Mar 31, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Marc G GhanyUNKNOWN American Association for the Study of Liver Diseases
Feb 19, 2013·Journal of Medical Virology·Giuseppe IndolfiMassimo Resti
Jun 1, 2000·The American Journal of Emergency Medicine·S Dorevitch, L Forst
Aug 25, 2004·Anesthesiology Clinics of North America·Arnold J Berry
Apr 6, 2016·Clinical and Molecular Hepatology·UNKNOWN Korean Association for the Study of the Liver
Apr 2, 2004·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Doris B StraderUNKNOWN American Association for the Study of Liver Diseases
May 13, 2005·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Scott D HalpernEmily Blumberg
Dec 31, 2014·Occupational Medicine·F Kevitt, B Hayes

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