Risk of hepatitis C virus transmission from an infected gynecologist to patients: results of a 7-year retrospective investigation

Archives of Internal Medicine
R Stefan RossArno Deister

Abstract

Currently, it is not known how often hepatitis C virus (HCV) is transmitted from infected health care workers to patients during medical care. In the present investigation, we tried to determine the rate of provider-to-patient transmission of HCV among former patients of an HCV-positive gynecologist after it was proven that he infected one of his patients with HCV during a cesarean section. All 2907 women who had been operated on by the HCV-positive gynecologist between July 1993 and March 2000 were notified about potential exposure and were offered free counseling and testing. The crucial differentiation between HCV transmissions caused by the gynecologist and infections contracted from other sources was achieved by epidemiological investigations, nucleotide sequencing, and phylogenetic analysis. Of the 2907 women affected, 78.6% could be screened for markers of HCV infection. Seven of these former patients were found to have HCV. Phylogenetic analysis of HCV sequences from the gynecologist and the women did not indicate that the virus strains were linked. Therefore, no further iatrogenic HCV infections caused by the gynecologist could be detected. The resulting overall HCV transmission rate was 0.04% (1 per 2286; 95% confiden...Continue Reading

Citations

Jul 15, 2003·Clinical Microbiology Reviews·David K Henderson
Apr 29, 2011·Journal of Virology·Sumathi RamachandranYury E Khudyakov
Jun 10, 2010·Surgical Infections·Arash MohebatiDonald E Fry
Nov 14, 2007·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·R S Ross
Jun 5, 2008·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M HickeyV Stearns
May 25, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·I T WilliamsB P Bell
Jul 20, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Yonat Shemer-AvniRan Tur-Kaspa
Feb 4, 2010·Clinics in Liver Disease·Abigail L Carlson, Trish M Perl
May 4, 2005·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Cherie Ng, John Swartzberg
Jun 27, 2002·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·William P Fiser
Jun 27, 2002·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Shirley PatonAntonio Giulivi
Feb 1, 2007·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Florence LotFrançoise Dumay
Jan 22, 2010·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·David K HendersonUNKNOWN Society for Healthcare Epidemiology of America
Jun 13, 2006·American Journal of Infection Control·Jane L PerryJanine Jagger
May 30, 2009·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Reinhard B RaggamHarald H Kessler
Feb 12, 2010·Journal of Health Services Research & Policy·Lee Salkeld, Sarah McGeehan
Oct 31, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Miriam J Alter
May 4, 2006·Journal of Pediatric Orthopedics·Ibrahim Al-HabdanMir Sadat-Ali
Dec 25, 2008·Journal of Medical Virology·R S RossO Janata
Dec 20, 2007·European Journal of Gastroenterology & Hepatology·Josep QuerMaria Martell
Nov 18, 2005·European Journal of Gastroenterology & Hepatology·Arne SchäferMichael R Kraus
Mar 30, 2010·Critical Reviews in Microbiology·Nazish Bostan, Tariq Mahmood
Oct 30, 2013·Journal of Medical Virology·David MuirAlison Holmes
Dec 18, 2014·World Journal of Gastroenterology : WJG·Bruno PozzettoPhilippe Berthelot
Oct 7, 2004·The Medical Journal of Australia·Katrina J R Watson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.