Risk of injury from acute alcohol consumption and the influence of confounders

Addiction
Kerrianne WattRoderick J McClure

Abstract

To quantify the relationship between acute alcohol consumption and risk of injury, in the context of other potential confounding factors (i.e. usual alcohol intake, risk-taking behaviour and substance use-defined as prescription/over-the-counter medication or illicit substances), using three separate measures of alcohol consumption. A hospital-based, case-control study. The accident and emergency department at a large metropolitan teaching hospital in Queensland, Australia. Four hundred and eighty-eight cases were matched to 488 population controls on gender, age group, neighbourhood, day and time of injury. Risk factor and injury information was obtained by questionnaire and medical record review. After controlling for demographic and situational variables (i.e. activity, location and companions at time of injury), consuming any alcohol in the 6 hours prior to time of injury significantly increased risk of injury [odds ratio (OR) = 2.13, 95% confidence interval (CI): 1.3-3.9]. Drinking at levels above low-risk guidelines for short-term health (i.e. drinking > 40 g alcohol per occasion if female, and drinking > 60 g alcohol if male) increased injury risk by a factor of almost 2.5 (OR = 2.41; 95% CI = 1.1-5.2). Finally, drinking...Continue Reading

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