Abstract
Previous reports on the risk of stroke after androgen deprivation therapy for prostate cancer were largely based on Caucasians. We investigated the risk of ischemic stroke after androgen deprivation therapy for prostate cancer in the Chinese population. All Chinese prostate cancer patients who were treated primarily with radical prostatectomy or radiotherapy, with (androgen deprivation therapy group) or without (non-androgen deprivation therapy group) further androgen deprivation therapy, at our hospital from year 2000-09 were reviewed. Potential risk factors of ischemic stroke including age, baseline prostate-specific antigen, Gleason score, clinical T stage, hypertension, diabetes mellitus, hyperlipidemia, ischemic heart disease, history of stroke, use of androgen deprivation therapy and duration of androgen deprivation therapy were reviewed. The risk of ischemic stroke after androgen deprivation therapy was analyzed with Kaplan-Meier and multivariate Cox regression analyses. A total of 452 patients were included, consisting of 200 patients in the non-androgen deprivation therapy group and 252 patients in the androgen deprivation therapy group. The androgen deprivation therapy group appeared to have increased risk of ischemic...Continue Reading
References
Feb 1, 1994·Diabetes·S M HaffnerM Laakso
Mar 1, 1997·Journal of Neuroendocrinology·D M ParryL M Glennie
Jul 31, 1997·The New England Journal of Medicine·M BollaM Pierart
May 23, 2002·CA: a Cancer Journal for Clinicians·Beth A Hellerstedt, Kenneth J Pienta
Jun 7, 2002·The Journal of Urology·Charles Huggins, Clarence V Hodges
Jul 20, 2002·Lancet·Michel BollaMarianne Pierart
Jan 14, 2005·The New England Journal of Medicine·Vahakn B ShahinianJames S Goodwin
Mar 3, 2005·Cancer·Vahakn B ShahinianJames S Goodwin
Jun 29, 2005·Diabetes Care·Nelly PitteloudFrances J Hayes
Jul 15, 2005·JAMA : the Journal of the American Medical Association·Nima SharifiWilliam L Dahut
Aug 24, 2005·Cancer·Hang LeeMatthew R Smith
Jan 26, 2006·The Journal of Clinical Endocrinology and Metabolism·Matthew R SmithDavid M Nathan
Jun 6, 2006·The Lancet Oncology·Edward M MessingUNKNOWN Eastern Cooperative Oncology Group study EST 3886
Sep 20, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Nancy L KeatingMatthew R Smith
Jul 28, 2007·Cancer·Christopher S SaigalUNKNOWN Urologic Diseases in America Project
Oct 11, 2007·Journal of the National Cancer Institute·Henry K TsaiPeter R Carroll
Mar 17, 2009·The Journal of Urology·Philip J Saylor, Matthew R Smith
Dec 10, 2009·Journal of the National Cancer Institute·Nancy L KeatingMatthew R Smith
Jun 23, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Mieke Van HemelrijckJan Adolfsson
Dec 8, 2010·Cerebrovascular Diseases·Pui Hing ChauSuzanne C Ho
Mar 10, 2011·International Journal of Cancer. Journal International Du Cancer·David RobinsonPär Stattin
Mar 30, 2011·European Journal of Endocrinology·Matthias MöhligChristof Schöfl
Jul 8, 2011·The Journal of Clinical Endocrinology and Metabolism·Geneviève NadeauEric Lévesque
Sep 3, 2011·BJU International·Shiu-Dong ChungHerng-Ching Lin
Sep 13, 2011·European Urology·Laurent AzoulaySamy Suissa
Dec 5, 2012·Journal of the National Cancer Institute·Nancy L KeatingMatthew R Smith
Feb 26, 2013·European Urology·Christina G JespersenMichael Borre
Aug 20, 2014·Prostate Cancer and Prostatic Diseases·A K MorgansD F Penson
Citations
Jun 4, 2016·International Urology and Nephrology·Jeremy Yuen Chun Teoh, Chi-Fai Ng
Nov 30, 2018·Asia-Pacific Journal of Clinical Oncology·Jeremy Yuen-Chun TeohDarren Ming-Chun Poon
Jun 12, 2019·Cancer Medicine·Bum Sik TaeJae Young Park
Jan 1, 2020·BMC Cancer·Kuang-Ming LiaoChen-Chun Kuo
Dec 14, 2019·Journal of Cardiovascular Translational Research·Chiara Melloni, Adam Nelson
Jul 15, 2015·Asian Pacific Journal of Cancer Prevention : APJCP·Xiao-Xia LiYan-Hua Shan
Oct 27, 2018·Therapeutic Advances in Drug Safety·M Reza SadaieGary A Thomas
Aug 30, 2020·Prostate Cancer and Prostatic Diseases·Hsiang Ying LeeHsiu-Mei Chang
Apr 15, 2021·Prostate Cancer and Prostatic Diseases·Joseph K M LiChi-Fai Ng
Jun 5, 2021·Frontiers in Pharmacology·Yi-Ting LinYu-Ning Chien
Sep 28, 2021·The Prostate·Jeremy Yuen-Chun TeohChi-Fai Ng
Nov 21, 2019·Urologia Internationalis·Ranlu LiuTao Li