PMID: 8601928Apr 10, 1996Paper

Risk of neural tube defect-affected pregnancies among obese women

JAMA : the Journal of the American Medical Association
G M ShawD M Schaffer

Abstract

To investigate the risk for neural tube defect (NTD)-affected pregnancies among obese women (ie, women with a body mass index [BMI] > 29kg/m2) compared with women of average prepregnancy weight. Population-based case-control study. All hospitals in 55 of 58 counties in California. In-person interviews were conducted with mothers of 538 (88% of eligible) NTD cases (including fetuses and infants electively terminated, stillborn, or born alive) and with mothers of 539 nonmalformed controls (88%) within an average of 5 months from the term delivery date. The risk of an NTD-affected pregnancy among obese women. Compared with women whose BMI was less than or equal to 29 kg/m2, an increased risk for NTD-affected pregnancy was observed among obese women (odds ratio, 1.9; 95% confidence interval, 1.3 to 2.9). The increased risk was not attributable to maternal nonuse of a vitamin containing folic acid, diabetes, use of diet pills, lower dietary folate intake, or an NTD-pregnancy history. Adjustment for maternal age, education, gravidity, use of vitamins, and use of alcohol did not change the odds ratio. The risk associated with maternal obesity was greater for spina bifida and for other less prevalent NTDs than for anencephaly. Because ...Continue Reading

Citations

Apr 23, 2008·European Journal of Endocrinology·Sarah J LewisGeorge Davey Smith
Jan 23, 2010·Obstetrics and Gynecology·Joseph R BiggioDwight J Rouse
May 30, 2001·Primary Care Update for Ob/Gyns·M E. CogswellW H. Dietz
Jan 18, 2008·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Christopher R J Woodhouse
Jan 24, 2008·Reproductive Sciences·Christina M DavidsonKit Sing Au
Jun 17, 2008·Epidemiology·Gary M Shaw, Suzan L Carmichael
Sep 25, 2008·Epidemiology·Aimin ChenWalter J Rogan
Jan 1, 2010·American Journal of Epidemiology·Mahsa M YazdyMartha M Werler
Apr 9, 2010·The American Journal of Clinical Nutrition·Richard H FinnellGary M Shaw
Sep 2, 2010·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Y S HanS S Lee
Dec 1, 2008·Journal of Clinical Research in Pediatric Endocrinology·Fima Lifshitz
Apr 1, 2009·Indian Journal of Clinical Biochemistry : IJCB·Supriya GuptaRitu Singh
Jul 6, 2004·American Journal of Epidemiology·Gary M ShawDonna M Schaffer
Apr 17, 2009·Journal of Occupational and Environmental Medicine·Adeleh ShirangiCarol Bower
Jun 21, 2001·Epidemiology·Margaret L. Watkins And, Lorenzo D. Botto
Dec 23, 2004·Epidemiology·James L AndersonMartha M Werler
Feb 24, 2009·Epidemiology·Suzan L CarmichaelGary M Shaw
May 27, 2005·Drugs·Mátyás TrixlerTamás Tényi
Jul 9, 2004·Toxicology and Applied Pharmacology·Richard H FinnellThomas H Rosenquist
May 17, 2003·Birth Defects Research. Part A, Clinical and Molecular Teratology·D Kim WallerAllen A Mitchell
Dec 26, 2001·Teratology·D K WallerA E Scheuerle
Sep 24, 2004·Obstetrical & Gynecological Survey·Elizabeth A McCarthyMichael Permezel
Apr 8, 2009·Therapeutic Drug Monitoring·Carolyn TamGideon Koren
Jan 25, 2002·American Journal of Medical Genetics·Gary M ShawCynthia A Moore
Dec 15, 2004·Clinical Obstetrics and Gynecology·Francis S Nuthalapaty, Dwight J Rouse
Dec 10, 2009·Current Opinion in Obstetrics & Gynecology·Joseph R Wax
Aug 31, 2006·Journal of Clinical Gastroenterology·Raymond J LynchRobert L Bell
Nov 5, 2013·Clinics in Perinatology·Jonathan R Swanson, Robert A Sinkin
Jun 21, 2012·Seminars in Perinatology·Diana RacusinKjersti M Aagaard
Jun 28, 2007·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Amy P CaseRebecca Wood
Feb 7, 2003·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Mary Carolan
Jul 16, 2005·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Lorraine O WalkerGayle M Timmerman
Oct 6, 1997·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·M B Tinkle, B S Sterling
Jul 31, 1998·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·K H Morin
Oct 2, 2015·American Journal of Epidemiology·Corey M BenedumMartha M Werler
Dec 20, 2007·Oral and Maxillofacial Surgery Clinics of North America·Thomas R Flynn, Srinivas M Susarla

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