Risk of ovarian torsion is reduced in GnRH agonist triggered freeze-all cycles: a retrospective cohort study

Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology
Murat BerkkanogluKemal Ozgur

Abstract

Ovarian torsion (OT) in IVF is rare, however, the consequences are significant, which include ovariotomy. In the present study, it was aimed for the first time to compare the incidence of OT between hCG triggered cycles with ICSI and fresh transfer and GnRH-agonist triggered cycles with the ICSI-freeze-all and frozen embryo transfer (FET). In total, 15,577 ICSI cycles performed between 2001 and 2016 were categorised into two groups (Group 1, n: 9978): cycles with controlled ovarian stimulation (COS) and hCG-triggered (Group 2, n: 5599) and COS, with GnRH-agonist only triggered and freeze-all. Thirteen patients (0.13%) were diagnosed with OT and corrected by laparoscopy (12) and laparotomy (1) in Group 1. One patient (0.018%) was diagnosed with OT and corrected by laparotomy in Group 2 (Group 1 vs. Group 2, p = .049). The incidence of severe ovarian hyperstimulation syndrome (OHSS) was 2.4% in Group 1 and 0.05% in Group 2 (p < .001). The use of freeze-all with GnRH agonist trigger in ART significantly reduced the incidence of OT and concomitantly OHSS, with no effect on the reproductive outcome. Impact Statement What is already known on this subject? Adnexal ovarian torsion (OT) is a well-known gynaecological event that constitu...Continue Reading

References

Jan 1, 1990·Fertility and Sterility·S MashiachZ Ben-Rafael
Jun 15, 1985·American Journal of Obstetrics and Gynecology·L T Hibbard
Jul 1, 1996·Human Reproduction Update·J RoestA Verhoeff
May 13, 1998·European Journal of Obstetrics, Gynecology, and Reproductive Biology·I GovaertsY Englert
Nov 1, 2002·Archives of Gynecology and Obstetrics·H GorkemliK Clasen
May 3, 2003·European Journal of Pain : EJP·Andrea KerschbaumerMichael Schirmer
Dec 4, 2003·Human Reproduction·Gabriel OelsnerHoward Carp
Dec 5, 2006·Fertility and Sterility·Beth W Rackow, Pasquale Patrizio
Nov 26, 2008·Fertility and Sterility·UNKNOWN Practice Committee of American Society for Reproductive Medicine
Apr 1, 2011·Human Reproduction Update·P HumaidanUNKNOWN Copenhagen GnRH Agonist Triggering Workshop Group
Apr 20, 2011·Human Reproduction·UNKNOWN Alpha Scientists in Reproductive Medicine and ESHRE Special Interest Group of Embryology
Dec 25, 2015·Journal of Assisted Reproduction and Genetics·Kemal OzgurKevin Coetzee
Nov 11, 2016·Journal of Assisted Reproduction and Genetics·Murat BerkkanogluKemal Ozgur

❮ Previous
Next ❯

Citations

Dec 24, 2019·Human Reproduction Update·Yossi MizrachiAriel Weissman
Nov 30, 2018·Journal of Assisted Reproduction and Genetics·Katrien StouffsChristophe Blockeel
Mar 27, 2020·Upsala Journal of Medical Sciences·Juan Carlos CastilloPeter Humaidan
Aug 28, 2021·Journal of Personalized Medicine·Jin-Sung YukMin-Sun Kyung

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.