Risk of second primary malignancies and causes of death in patients with adenocarcinoma and carcinoid of the small intestine

European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
Niklas ZarPer Hellman

Abstract

We studied risk of second malignancies and causes of death in 1829 cases of adenocarcinoma and 3055 cases of carcinoid tumours in the small bowel reported to the Swedish Cancer Registry from 1960 through to 2000. Data on causes of death were analysed as from 1966 whereas data on second tumours was available during the whole registry-period. Follow-up was available until 2001. Standard mortality ratio (SMR) and standard incidence ratio (SIR) were calculated. Female patients with adenocarcinoma had increased risk of acquiring cancer in the female genital organs (SIR 3.2; 95% confidence intervals (CI) 1.9-5.0) and breasts (SIR 2.7; 95% CI 1.1-5.4). Both sexes combined had increased risk of second tumours in the gastrointestinal tract (SIR 1.5; 95% CI 1.1-2.1) and skin (SIR 4.6; 95% CI 1.2-12). Men with carcinoid tumour had increased risk of prostate cancer (SIR 2.8; 95% CI 1.6-4.6). Increased risk was seen for both sexes with carcinoid for malignant melanoma (SIR 6.3; 95% CI 2.7-12), malignant skin tumours (SIR 3.6; 95% CI 1.7-6.7) and malignancies of endocrine organs (SIR 2.3 95% CI 1.3-3.8). Patients with adenocarcinoma had increased risk of dying from malignant diseases other than the primary cancer (SMR 9.5; 95% CI 8.6-10) and...Continue Reading

References

Mar 1, 1993·Cancer Causes & Control : CCC·W H ChowW J Blot
Apr 1, 1993·International Journal of Epidemiology·S GabosH Whittaker
Nov 1, 1996·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·N ZarJ Rastad
Sep 29, 2001·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·K Hemminki, Y Jiang
Feb 6, 2003·Cancer·Irvin M ModlinMark Kidd
Mar 12, 2003·The Journal of Urology·Camilla ThellenbergHenrik Grönberg
Jul 9, 2005·International Journal of Cancer. Journal International Du Cancer·Ghislaine ScéloPaul Brennan
Jun 1, 1968·Annals of Surgery·J W Alexander, W A Altemeier

❮ Previous
Next ❯

Citations

Jan 20, 2009·Annals of Oncology : Official Journal of the European Society for Medical Oncology·E HiripiK Hemminki
Oct 3, 2013·PloS One·Mieke Van HemelrijckJan Adolfsson
Jul 23, 2014·PloS One·Mieke Van HemelrijckSabine Rohrmann
Jan 1, 2014·World Journal of Gastroenterology : WJG·Hans ScherüblSören M Zappe
Oct 29, 2013·Expert Review of Gastroenterology & Hepatology·Nivedita BasuLisa A Boardman
Oct 22, 2015·Annals of Oncology : Official Journal of the European Society for Medical Oncology·Emanuele LeonciniGuido Rindi
Sep 14, 2013·Gastroenterología y hepatología·Edel Berroa de la RosaLuis Fernández Salazar
Mar 6, 2012·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Andreas ThorstensonJan Adolfsson
Jun 23, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Mieke Van HemelrijckJan Adolfsson
Aug 29, 2013·World Journal of Gastrointestinal Surgery·Danielle M HariFarin Amersi
Dec 3, 2016·Annals of Surgical Oncology·John ErikssonCatharina Ihre-Lundgren
Oct 8, 2019·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·J ErikssonP Hellman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Scandinavian Journal of Urology and Nephrology
Eva HagelPär Stattin
European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
Andreas ThorstensonJan Adolfsson
© 2021 Meta ULC. All rights reserved