Risk of senile cataract among nuclear industry workers

Vestnik oftalmologii
E V BraginM V Bannikova

Abstract

to assess the relative risk (RR) of senile cataract in a cohort of workers occupationally exposed to external gamma-rays over a long time period. The RR of cataract development was studied in a cohort of nuclear workers that were first employed in 1948-1982 and followed up till the end of 2008 (n=22,377; females, 25.4%). The mean age at initial employment was 24.9 years. The mean cumulative gamma-ray dose was 0.54 Sv in males and 0.44 Sv in females. The analysis performed with EPICURE software provided RR estimates for cataract incidence in relation to a number of non-radiation and radiation factors. The RR of senile cataract increased with the attained age of the workers. The RR was significantly higher in males during the 2006-2008 period as compared to the 1996-2005 period. The RR was significantly higher in workers that were diagnosed with glaucoma and high myopia as compared to those that were not. The risk of senile cataract increased with the external gamma-ray dose and was the highest in workers who had formerly been exposed to doses above 2.00 Sv. The RR of senile cataract showed no dependency on sex, age at initial employment, smoking status, alcohol consumption, or diabetes mellitus. The incidence of senile cataract ...Continue Reading

References

Jan 1, 1989·Developments in Ophthalmology·J J Harding, R van Heyningen
May 24, 2001·The British Journal of Ophthalmology·A Foster
Feb 24, 2004·Ophthalmic Epidemiology·Martha Savaria MorrisAllen Taylor
May 27, 2004·Radiation Research·Michiko YamadaGen Suzuki
Jun 30, 2004·International Journal of Radiation Biology·A MinamotoM Akahoshi
Jan 13, 2006·Health Physics·Eiji NakashimaAtsushi Minamoto
Oct 28, 2006·Ophthalmology Clinics of North America·Alison G AbrahamEmily West Gower
Dec 19, 2006·Ophthalmology·Birgitta Ejdervik LindbladAlicja Wolk
Nov 21, 2007·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·J J Navarro EstebanV Martínez-Vizcaíno
Jun 24, 2008·Ophthalmic Epidemiology·Jennifer S L TanPaul Mitchell
Sep 2, 2009·Acta Ophthalmologica·Gijs F J M Vrensen
Jan 13, 2010·Acta Ophthalmologica·Sofia TheodoropoulouAnastasia Tzonou
Aug 11, 2010·Archives of Ophthalmology·Renyi WuTien Yin Wong

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