PMID: 9192214Jan 1, 1997Paper

Risk of spontaneous abortion and maternal exposure to organic solvents in the shoe industry

International Archives of Occupational and Environmental Health
R AgnesiG Mastrangelo

Abstract

A high risk of spontaneous abortion was observed in women exposed to organic solvents during pregnancy. Since this risk was not found in the shoe industry, where these solvents are widely used, we carried out a case-control study on the risk of spontaneous abortion in a health district (Veneto, Northern Italy) where about 8,000 people work in shoe manufacturing. Aliphatic hydrocarbons were generally used; their concentrations were repeatedly below the mixture TLVs in the observation period. Cases (clinically recognized spontaneous abortion, ICD codes 632-634-636) and age-/year-/residence-matched controls (admitted for normal delivery) were traced in the files of the regional hospital discharges register. Data on 108 cases (81% response) and the same number of reference subjects were collected on questionnaires completed by nurses trained in occupational medicine. There were questions on confounding and occupational factors, and an open question to ensure a complete description of work done during pregnancy. An occupational physician, working blind, then coded exposure to organic solvents according to a three-level polytomous variable (no, low, high exposure). The cases/controls not exposed, exposed to low levels and exposed to ...Continue Reading

Citations

Jun 18, 2011·International Archives of Occupational and Environmental Health·Mir Saeed AttarchiSaber Mohammadi
Jan 4, 2003·Archives of Environmental Health·Eunhee HaDavid C Christiani
May 13, 2008·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Donald T WigleDaniel Krewski
Jun 11, 2010·European Journal of Public Health·Roberto AgnesiGiuseppe Mastrangelo
Mar 14, 2001·Occupational and Environmental Medicine·J J Kurinczuk, M Clarke
Feb 13, 2014·American Journal of Epidemiology·Beth L PinelesJonathan M Samet
Mar 28, 2008·International Journal of Environmental Health Research·Arild VaktskjoldEvert Nieboer
May 15, 2001·Regulatory Toxicology and Pharmacology : RTP·J A Bukowski
Nov 16, 2010·BMC Public Health·Giuseppe MastrangeloLuca Cegolon
Jan 9, 2007·New Solutions : a Journal of Environmental and Occupational Health Policy : NS·Pia Markkanen, Charles Levenstein
Jun 11, 1999·American Journal of Industrial Medicine·A SeidlerF W Schwartz
Mar 17, 2020·The Journal of Obstetrics and Gynaecology Research·Shashi Nandar KumarArun Kumar Jain

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