Risk of subsequent primary neoplasms in survivors of adolescent and young adult cancer (Teenage and Young Adult Cancer Survivor Study): a population-based, cohort study.

The Lancet Oncology
Chloe J BrightMichael M Hawkins

Abstract

Few studies have investigated the risks of subsequent primary neoplasms after adolescent and young adult (AYA) cancer. We investigated the risks of specific subsequent primary neoplasms after each of 16 types of AYA cancer. The Teenage and Young Adult Cancer Survivor Study is a population-based cohort of 200 945 survivors of cancer diagnosed when aged 15-39 years in England and Wales from Jan 1, 1971, to Dec 31, 2006. The cohort was established using cancer registrations from the Office for National Statistics and the Welsh Cancer registry. Follow-up was from 5-year survival until the first occurrence of death, emigration, or study end date (Dec 31, 2012). In this analysis, we focus on the risk of specific subsequent primary neoplasms after 16 types of AYA cancer: breast; cervical; testicular; Hodgkin lymphoma (female); Hodgkin lymphoma (male); melanoma; CNS (intracranial); colorectal; non-Hodgkin lymphoma; thyroid; soft-tissue sarcoma; ovarian; bladder; other female genital; leukaemia; and head and neck cancer. We report absolute excess risks (AERs; per 10 000 person-years) and cumulative incidence of specific types of subsequent primary neoplasm after each type of AYA cancer. During the 2 631 326 person-years of follow-up (me...Continue Reading

Citations

Apr 6, 2019·British Journal of Hospital Medicine
Jan 17, 2020·BMJ : British Medical Journal·Mike HawkinsRaoul Reulen
Aug 5, 2020·Journal of Adolescent and Young Adult Oncology·Andreana N HolowatyjCornelia M Ulrich
Apr 22, 2020·Clinical Pediatric Endocrinology : Case Reports and Clinical Investigations : Official Journal of the Japanese Society for Pediatric Endocrinology·Yoko MiyoshiKeiichi Ozono
May 13, 2020·Leukemia·Andishe AttarbaschiUNKNOWN European Intergroup for Childhood Non-Hodgkin’s Lymphoma (EICNHL) and the International Berlin-Frankfurt-Münster (i-BFM) Stu
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Mar 2, 2021·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·S MassironiUNKNOWN ItaNet (Italian Association for Neuroendocrine Tumours) Study Group
Mar 19, 2021·Blood·Nancy L Bartlett
Mar 19, 2021·Journal of Cancer Survivorship : Research and Practice·Rachel TillerySean Phipps
Nov 3, 2020·Pediatric Clinics of North America·Michael HawkinsLindsay M Morton
Apr 14, 2021·Journal of Adolescent and Young Adult Oncology·Ivana Bozovic-SpasojevicDaniel Stark
Apr 6, 2021·Pediatric Blood & Cancer·Joshua D PalmerLouis S Constine
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