Risk of subsequent tumour recurrence and stage progression in bacille Calmette-Guérin relapsing non-muscle-invasive bladder cancer

BJU International
Kazuhiro MatsumotoMototsugu Oya

Abstract

What's known on the subject? and What does the study add? So far, few previous reports have analysed the risk factors for tumour recurrence and stage progression with a special focus on BCG-relapsing disease, defined as the recurrence after achieving a disease-free status by initial BCG instillations for 6 months. There are no guidelines outlining a specific treatment strategy for BCG-relapsing disease, although many BCG failure cases are attributable to BCG-relapsing disease. In this study, additional BCG instillation was shown to decrease the subsequent tumour recurrence rate against BCG-relapsing tumours with intermediate pathological risk features; however, a BCG-relapsing tumour with a pathologically high risk was a significant risk factor for both subsequent tumour recurrence and stage progression. This information might identify a therapeutic strategy for BCG-relapsing tumours. • To investigate the risk of subsequent tumour recurrence and stage progression in bacillus Calmette-Guérin (BCG)-relapsing non-muscle-invasive bladder cancer, defined as recurrence after achieving a disease-free status for 6 months. • A total of 183 patients with BCG-relapsing tumours were treated with conservative therapy between 1985 and 2008 a...Continue Reading

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Apr 5, 2011·European Urology·Marko BabjukUNKNOWN European Association of Urology (EAU)

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Citations

Jan 9, 2020·The Cochrane Database of Systematic Reviews·Stefanie SchmidtJoerg J Meerpohl
Dec 4, 2019·International Journal of Urology : Official Journal of the Japanese Urological Association·Eiji KikuchiKazuhiro Matsumoto

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