PMID: 8980976Dec 1, 1996Paper

Risk of traffic accidents in patients with sleep-disordered breathing: reduction with nasal CPAP

The European Respiratory Journal
W CasselP von Wichert

Abstract

Sleepiness whilst driving constitutes a road safety risk. Sleep-related breathing disorders are the most frequent medical cause of daytime sleepiness, and untreated patients with this condition have been shown to be at a higher risk of having accidents while driving. This study addressed the question of the extent to which treatment of sleep-disordered breathing by nasal continuous positive airway pressure (nCPAP) is related to changes in patient's accident risk. Seventy eight male patients requiring treatment of sleep-related breathing disorders with nCPAP were enrolled in the study. The protocol included a questionnaire dealing with alertness-related problems while driving, an 80 min vigilance test, and the Multiple Sleep Latency Test. These baseline evaluations were repeated after 1 year of treatment with nCPAP. Fifty nine patients completed the study. The accident rate was significantly decreased from 0.8 per 100,000 km (untreated) to 0.15 per 100,000 km with nCPAP treatment. Variables that were considered to be likely to increase accident risk (sleeping spells, fatigue, vigilance test reaction time, daytime sleep latency) also improved with treatment. We conclude that treatment of sleep-disordered breathing by nasal contin...Continue Reading

Citations

Jun 21, 2002·Sleep & Breathing = Schlaf & Atmung·Jamil L Hossain, Colin M Shapiro
Feb 21, 2009·Sleep & Breathing = Schlaf & Atmung·Mohsen SadatsafaviJohn Fleetham
Oct 20, 2011·Sleep & Breathing = Schlaf & Atmung·Carlos Alberto NigroEdgardo Rhodius
Aug 18, 2004·Sleep Medicine Reviews·H Engleman, D Joffe
Sep 9, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·R ConradtJ H Peter
Jun 29, 2002·Internal Medicine Journal·B YeeA Neill
Feb 8, 2002·The New England Journal of Medicine·Stephane GarrigueJacques Clementy
Dec 4, 2010·Traffic Injury Prevention·M Fadhli Mohd YusoffAzlan I Ishak
Nov 14, 2001·Current Opinion in Pulmonary Medicine·R Zozula, R Rosen
Jul 9, 1998·American Journal of Respiratory and Critical Care Medicine· BarbéA G Agustí
Mar 11, 2000·American Journal of Respiratory and Critical Care Medicine·L FindleyP M Suratt
Mar 19, 2002·American Journal of Respiratory and Critical Care Medicine·Charles F P GeorgeR Douglas McEvoy
Feb 6, 2008·Proceedings of the American Thoracic Society·Mark H SandersRachel J Givelber
Jun 17, 2011·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Andrew VakulinR Doug McEvoy
Oct 16, 2013·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Kim L WardSutapa Mukherjee
Jan 25, 2007·Sleep & Breathing = Schlaf & Atmung·Aarnoud HoekemaJohannes H van der Hoeven
Mar 1, 2012·Journal of Perinatology : Official Journal of the California Perinatal Association·A M FungS P Walker
Mar 19, 2008·Chest·Evangelia NenaDemosthenes Bouros
Dec 10, 2013·Industrial Health·Stefanos N Kales, Madeleine G Straubel
Mar 5, 2016·Lung India : Official Organ of Indian Chest Society·Vitaliano Nicola QuarantaOnofrio Resta
Dec 7, 2010·Accident; Analysis and Prevention·Ann WilliamsonJennie L Connor
Sep 19, 2009·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Richard M Dasheiff, Richard Finn
Sep 4, 2007·Sleep Medicine·A AlonderisUNKNOWN COST Action B-26
May 28, 2008·Journal of Sleep Research·Carolina LombardiPaolo Castiglioni
Jul 25, 2008·Journal of Sleep Research·Daniel Rodenstein, UNKNOWN Cost-B26 Action on Sleep Apnoea Syndrome
Jan 25, 2008·Accident; Analysis and Prevention·Indira GurubhagavatulaAllan I Pack
Jul 6, 2004·Sleep Medicine Reviews·Valérie Wittmann, Daniel O Rodenstein
Apr 29, 1998·Clinics in Chest Medicine·A Bahammam, M Kryger
Apr 10, 1999·Neurologic Clinics·M W Mahowald, C H Schenck
Mar 20, 2003·Accident; Analysis and Prevention·Jane C StuttsBradley V Vaughn
Dec 25, 2012·Accident; Analysis and Prevention·Mahssa KarimiLudger Grote
Jan 18, 2003·Sleep Medicine Reviews·José M MontserratDaniel O Rodenstein
Jan 18, 2003·Sleep Medicine Reviews·Elizabeth Ellis, Ronald R. Grunstein
Jul 16, 1999·Progress in Cardiovascular Diseases·R DayL Rosenthal

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.