Risk prediction models for contrast induced nephropathy: systematic review

BMJ : British Medical Journal
Samuel A SilverZiv Harel

Abstract

To look at the available literature on validated prediction models for contrast induced nephropathy and describe their characteristics. Systematic review. Medline, Embase, and CINAHL (cumulative index to nursing and allied health literature) databases. Databases searched from inception to 2015, and the retrieved reference lists hand searched. Dual reviews were conducted to identify studies published in the English language of prediction models tested with patients that included derivation and validation cohorts. Data were extracted on baseline patient characteristics, procedural characteristics, modelling methods, metrics of model performance, risk of bias, and clinical usefulness. Eligible studies evaluated characteristics of predictive models that identified patients at risk of contrast induced nephropathy among adults undergoing a diagnostic or interventional procedure using conventional radiocontrast media (media used for computed tomography or angiography, and not gadolinium based contrast). 16 studies were identified, describing 12 prediction models. Substantial interstudy heterogeneity was identified, as a result of different clinical settings, cointerventions, and the timing of creatinine measurement to define contrast ...Continue Reading

Citations

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