Risk profiles and pattern of antithrombotic use in patients with non-valvular atrial fibrillation in Thailand: a multicenter study

BMC Cardiovascular Disorders
Rungroj KrittayaphongCOOL-AF Investigators

Abstract

Anticoagulation therapy is a standard treatment for stroke prevention in patients with non-valvular atrial fibrillation (NVAF) that have risk factors for stroke. However, anticoagulant increases the risk of bleeding, especially in Asians. We aimed to investigate the risk profiles and pattern of antithrombotic use in patients with NVAF in Thailand, and to study the reasons for not using warfarin in this patient population. A nationwide multicenter registry of patients with NVAF was created that included data from 24 hospitals located across Thailand. Demographic data, atrial fibrillation-related data, comorbid conditions, use of antithrombotic drugs, and reasons for not using warfarin were collected. Data were recorded in a case record form and then transferred into a web-based system. A total of 3218 patients were included. Average age was 67.3 ± 11.3 years, and 58.2% were male. Average CHADS2, CHA2DS2-VASc, and HAS-BLED score was 1.8 ± 1.3, 3.0 ± 1.7, and 1.5 ± 1.0, respectively. Antiplatelet was used in 26.5% of patients, whereas anticoagulant was used in 75.3%. The main reasons for not using warfarin in those with CHA2DS2-VASc ≥2 included already taking antiplatelet (26.6%), patient preference (23.1%), and using non-vitamin ...Continue Reading

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Citations

May 12, 2020·Stroke; a Journal of Cerebral Circulation·Rungroj KrittayaphongUNKNOWN COOL-AF Investigators
Apr 7, 2019·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Varalak SrinonprasertUNKNOWN COOL AF Investigators
Aug 29, 2020·British Journal of Clinical Pharmacology·Phannita WattanaruengchaiGregory Y H Lip
Aug 28, 2020·Journal of Clinical Medicine·Rungroj KrittayaphongGregory Y H Lip
Dec 29, 2020·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Eyob Alemayehu GebreyohannesKenneth Lee
Feb 5, 2021·Clinical Cardiology·Rungroj KrittayaphongUNKNOWN COOL-AF Investigators
May 7, 2021·Clinical Interventions in Aging·Rungroj KrittayaphongUNKNOWN COOL-AF Investigators
Aug 28, 2021·European Heart Journal. Acute Cardiovascular Care·Ply ChichareonSaranyou Suwanugsorn

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