Risk Scoring Systems Including Electrolyte Disorders for Predicting the Incidence of Acute Kidney Injury in Hospitalized Patients.

Clinical Epidemiology
Xin ChenWuhua Jiang

Abstract

Electrolyte disorders are common among hospitalized patients with acute kidney injury (AKI) and adversely affect the outcome. This study aimed to explore the potential role of abnormal electrolyte levels on predicting AKI and severe AKI. In this retrospective, observational study, we included all hospitalized patients in our hospital in China from October 01, 2014, to September 30, 2015. Since only a few patients had arterial blood gas analysis (ABG), all subjects involved were divided into two groups: patients with ABG and patients without ABG. Severe AKI was defined as AKI stage 2 or 3 according to KDIGO guideline. A total of 80,091 patients were enrolled retrospectively and distributed randomly into the test cohort and the validation cohort (2:1). Logistic regression was performed in the test cohort to analyze risk factors including electrolyte disorders and elucidate the association. The test data (derivation cohort) led to AUC values of 0.758 (95% CI: 0.743-0.773; AKI with ABG), 0.751 (95% CI: 0.740-0.763; AKI without ABG), 0.733 (95% CI: 0.700-0.767; severe AKI with ABG), 0.853 (95% CI: 0.824-0.882; severe AKI without ABG). Application of the scoring system in the validation cohort led to AUC values of 0.724 (95% CI: 0.70...Continue Reading

References

Jul 25, 1996·The New England Journal of Medicine·D C Jones, J P Hayslett
May 27, 2003·Reviews in Endocrine & Metabolic Disorders·Joel Michels Topf, Patrick T Murray
Nov 11, 2003·Journal of the American College of Cardiology·C Michael GibsonUNKNOWN TIMI Study Group
Nov 26, 2004·Journal of the American Society of Nephrology : JASN·Charuhas V ThakarEmil P Paganini
Apr 27, 2005·Lancet·David A Grimes, Kenneth F Schulz
Sep 24, 2005·Journal of the American Society of Nephrology : JASN·Glenn M ChertowDavid W Bates
Apr 28, 2007·Contributions to Nephrology·Prasad Devarajan
Mar 14, 2008·Clinical Journal of the American Society of Nephrology : CJASN·Michael BennettPrasad Devarajan
May 6, 2009·Annals of Internal Medicine·Andrew S LeveyUNKNOWN CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration)
Apr 1, 2010·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Michael E MathenyJosh F Peterson
Aug 18, 2010·Blood Purification·Yi FangPan Lin
Jul 6, 2012·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Sarah Cascaes AlvesCristiane Ritter
Sep 12, 2012·Journal of Manipulative and Physiological Therapeutics·David VergouwHenrica C W de Vet
Jun 8, 2013·Clinical Journal of the American Society of Nephrology : CJASN·Paweena SusantitaphongUNKNOWN Acute Kidney Injury Advisory Group of the American Society of Nephrology
Jun 24, 2015·Renal Failure·Wisit CheungpasitpornStephen B Erickson
Jul 15, 2015·Australian Critical Care : Official Journal of the Confederation of Australian Critical Care Nurses·Wendy J DunnTanya L Woods
Jun 9, 2016·European Journal of Epidemiology·Kenneth J Rothman
Aug 6, 2016·Journal of the American Heart Association·Wuhua JiangXiaoqiang Ding
Oct 8, 2016·Critical Care : the Official Journal of the Critical Care Forum·Bandarn SuetrongKeith R Walley
Apr 13, 2017·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Rakesh MalhotraRavindra Mehta
Jun 2, 2017·Experimental and Therapeutic Medicine·Jiachang HuXiaoqiang Ding
Sep 7, 2017·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Tsung-Yu TsaiYung-Chang Chen
Jul 11, 2018·Acute Medicine & Surgery·Mana NishikawaKenichiro Asano
Dec 12, 2018·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Yimei WangXiaoqiang Ding

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