Risk stratification and detection of new colorectal neoplasms after colorectal cancer screening with faecal occult blood test: experiences from a Danish screening cohort

European Journal of Gastroenterology & Hepatology
Andreas BjerrumElsebeth Lynge

Abstract

Limited data exist on adenoma surveillance as recommended in the European guidelines for quality assurance in colorectal cancer (CRC) screening and diagnosis after faecal occult blood test (FOBT) screening. To assess the European guidelines for adenoma surveillance after CRC screening with FOBT. This was a population-based cohort-study of 176 782 Danish individuals aged 50-74 years invited for CRC screening in 2005-2006. Adenoma patients were stratified into risk groups (low A, medium B, high C) in accordance with the European guidelines and followed up for recurrence of new neoplasms until the end of 2011. Risk ratios (RR) between the risk groups were calculated to assess differences in the recurrence rates of neoplasms. Among 84 803 screening participants, 2059 had positive FOBT, of whom 1861 underwent colonoscopy, and 709 patients had screen-detected adenomas. During a median follow-up period of 72.7 months, detection of new advanced adenomas (B+C) was significantly higher in risk group C than group A (RR 2.25, 95% confidence interval: 1.13-4.48). Nine patients were diagnosed with CRC: one in risk group A, two in B and six in C. The detection rate of CRC was higher in risk group C than A (RR 5.20, 95% confidence interval: 0....Continue Reading

References

Dec 1, 1975·Cancer·T MutoB C Morson
Jul 21, 1994·The New England Journal of Medicine·E R GreenbergR W Haile
Sep 1, 1996·Scandinavian Journal of Gastroenterology·G HoffM H Vatn
Feb 11, 2000·Annals of the New York Academy of Sciences·J A BaronE R Greenberg
Apr 2, 2004·Gastroenterology·M E MartínezD S Alberts
Sep 11, 2002·Gut·W S AtkinUNKNOWN Association of Coloproctology for Great Britain and Ireland
Mar 7, 2003·The New England Journal of Medicine·John A BaronRosalind U van Stolk
Jun 2, 2005·Journal of the National Cancer Institute·David S AlbertsUNKNOWN Phoenix and Tucson Gastroenterologist Networks
Aug 19, 2007·Gastroenterology·David A LiebermanDouglas Robertson
Sep 2, 2008·Zeitschrift für Gastroenterologie·W SchmiegelC Pox
Jan 28, 2009·Gastroenterology·María Elena MartínezE Robert Greenberg
Feb 24, 2012·The New England Journal of Medicine·Ann G ZauberJerome D Waye
Jun 25, 2013·Gut·Douglas J RobertsonMaría Elena Martínez
Aug 28, 2014·The New England Journal of Medicine·Magnus LøbergMichael Bretthauer

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Citations

Jul 10, 2018·European Journal of Public Health·Isabel PortilloUNKNOWN EUSKOLON Study Investigators
Jan 3, 2020·International Journal of Cancer. Journal International Du Cancer·Andreas BjerrumElsebeth Lynge
Sep 14, 2018·Endoscopy International Open·Isabel PortilloUNKNOWN EUSKOLON study investigators
Aug 21, 2021·Journal of the National Comprehensive Cancer Network : JNCCN·Reece J Knippel, Cynthia L Sears
Mar 30, 2021·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Charles J KahiThomas F Imperiale

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