Risk stratification and venous thromboprophylaxis in hospitalized medical and cancer patients

British Journal of Haematology
P Prandoni, Michel M Samama

Abstract

Acute venous thromboembolism (VTE) is a serious and potentially fatal disorder, which often complicates the course of hospitalized medical patients. This is particularly true for carriers of malignant diseases. While the introduction of thromboprophylactic measures has probably affected the occurrence of postoperative VTE, there is an increasing awareness of the importance of medical conditions in determining thromboembolic events. Simple and clinically relevant risk assessment models are available to facilitate VTE risk assessment in hospitalized medical patients. Their validation in prospective studies is in progress. Randomized controlled clinical trials have consistently documented the efficacy of heparins and fondaparinux for prevention of VTE in hospitalized medical patients with a minimal haemorrhagic risk. Recognition of the incidence and clinical importance of thrombosis will probably encourage more widespread use of antithrombotic prophylaxis in medical patients and especially in some particular types of malignancies.

References

Aug 1, 1992·Journal of Internal Medicine·M NordströmT Kjellström
Mar 15, 1973·The New England Journal of Medicine·A S GallusS M Hudecki
May 1, 1982·Annals of Internal Medicine·H HalkinB Modan
Jul 1, 1980·Southern Medical Journal·V S Shen, E W Pollak
Jul 20, 1996·Lancet·J F Bergmann, C Caulin
Apr 29, 1998·The New England Journal of Medicine·H T SørensenG L Nielsen
Jul 11, 1998·Lancet·J A BaronM Linet
Nov 10, 2001·Human Genetics·R F Franco, P H Reitsma
Jun 1, 2002·Archives of Internal Medicine·John A HeitL Joseph Melton
Aug 5, 2003·The Oncologist·Ajay K KakkarJohn Wong
Sep 27, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Melina Verso, Giancarlo Agnelli
Jan 13, 2004·The American Journal of Cardiology·Samuel Z GoldhaberUNKNOWN DVT FREE Steering Committee
Mar 12, 2004·The New England Journal of Medicine·R Charles CoombesUNKNOWN Intergroup Exemestane Study
May 15, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ajay K KakkarRobin C N Williamson
Jun 24, 2004·Thrombosis and Haemostasis·Alexander G G Turpie, Timothy M Norris
Aug 4, 2004·Circulation·Alain LeizoroviczUNKNOWN PREVENT Medical Thromboprophylaxis Study Group
Dec 23, 2004·Journal of Thrombosis and Haemostasis : JTH·G J MillerR D Rosenberg
Dec 23, 2004·Journal of Thrombosis and Haemostasis : JTH·N A ZakaiM Cushman
Feb 9, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Clara P W KlerkHarry R Büller
Feb 9, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Agnes Y Y LeeMark N Levine
Feb 11, 2005·JAMA : the Journal of the American Medical Association·Jeanet W BlomFrits R Rosendaal
Mar 11, 2005·The New England Journal of Medicine·Nils KucherSamuel Z Goldhaber
Mar 16, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Stephen CoubanDavid R Anderson
Mar 16, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Melina VersoStefano Mosca
Mar 18, 2005·Nature·Carla BoccaccioPaolo M Comoglio
Mar 25, 2005·Journal of Internal Medicine·P ChopardH Bounameaux
Apr 29, 2005·International Journal of Clinical Practice·J-F Bergmann, A Kher
Jun 1, 2005·The Lancet Oncology·Paolo PrandoniAndrea Piccioli
Aug 10, 2005·Archives of Internal Medicine·Richard H WhiteTheodore Wun
Sep 2, 2005·British Journal of Cancer·H T SørensenJ A Baron
Dec 1, 2005·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M KarthausP Reichardt
Jan 25, 2006·The American Journal of Medicine·Paul D SteinRonald E Olson

❮ Previous
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Citations

Oct 16, 2009·Annals of Oncology : Official Journal of the European Society for Medical Oncology·N KucherH Bounameaux
Jul 14, 2009·Current Opinion in Pulmonary Medicine·Giuseppe Camporese, Enrico Bernardi
Feb 25, 2014·Techniques in Coloproctology·H H EremJ D Vogel
Oct 17, 2017·Clinical Chemistry and Laboratory Medicine : CCLM·Maria Filomena RubertoDoris Barcellona
Sep 4, 2019·Journal of Thrombosis and Haemostasis : JTH·Lorenzo GervasoAlok A Khorana
May 8, 2020·Circulation·Peter K HenkeUNKNOWN American Heart Association Advocacy Coordinating Committee
Mar 3, 2012·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Alexandra Brown
Jan 8, 2013·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Charles E Mahan, Alex C Spyropoulos
Sep 2, 2017·Journal of Thrombosis and Thrombolysis·Hikmat Abdel-Razeq, Asem Mansour
Feb 12, 2017·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Hikmat Abdel-RazeqMohammad Ibrahim
Jun 10, 2018·Blood Cancer Journal·Stefan HohausValerio De Stefano
Jan 11, 2021·Thrombosis Research·Tarek HaykalThomas L Ortel
Sep 12, 2021·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Tarek HaykalThomas L Ortel

❮ Previous
Next ❯

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