Abstract
It was the aim of this study to compare the prognostic impact of echocardiography and brain natriuretic peptide and its N-terminal fragment (NT-proBNP) in patients with chronic heart failure (CHF). In all, 73 patients with CHF underwent conventional 2-dimensional/Doppler echocardiography and Doppler tissue analysis of systolic, early and late diastolic mitral annular velocities. The mitral filling pattern was classified as restrictive or nonrestrictive. NT-proBNP measurements were carried out on a bench-top analyzer. A cardiac event (rehospitalization caused by worsening CHF, cardiac death, urgent cardiac transplantation) was defined as combined study end point. During follow-up of 226 +/- 169 days, 27 patients had an event (rehospitalization because of CHF, n = 18; cardiac death, n = 7; urgent transplantation, n = 2). On multivariate Cox regression analysis, a restrictive filling pattern, NT-proBNP, the ratio of peak early diastolic mitral flow to mitral annular E' velocity were independent prognostic predictors. A risk stratification model based on the 3 strongest independent predictors separated groups into those with good, intermediate, and poor outcome (event-free survival of 78%, 46%, and 0%, respectively). In patients wi...Continue Reading
References
Mar 11, 1991·Circulation·D M ManciniJ R Wilson
Jul 15, 1997·Circulation·T TsutamotoM Kinoshita
Nov 15, 1997·Journal of the American College of Cardiology·S F NaguehM A Quiñones
Jun 17, 1998·Journal of the American College of Cardiology·P L TemporelliP Giannuzzi
Oct 12, 2000·Circulation·S R OmmenA J Tajik
Jun 2, 2001·The New England Journal of Medicine·M PackerUNKNOWN Carvedilol Prospective Randomized Cumulative Survival Study Group
Jun 19, 2001·Heart·T A McDonaghH J Dargie
Mar 12, 2003·Journal of the American College of Cardiology·Mei WangJohn E Sanderson
Mar 14, 2003·The American Journal of Cardiology·Carlos Rivas-GotzSherif F Nagueh
Aug 23, 2003·Journal of the American College of Cardiology·John G LainchburyA Mark Richards
Oct 3, 2003·European Heart Journal·M R CowieG Francis
Oct 3, 2003·European Heart Journal·R S GardnerT A McDonagh
Mar 12, 2004·Journal of the American College of Cardiology·Graham S HillisJae K Oh
Oct 13, 2004·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Markus RothenburgerHans Heinrich Scheld
Aug 6, 2005·International Journal of Cardiology·Tayfun AcilChristian Bruch
Citations
Oct 30, 2012·European Heart Journal Cardiovascular Imaging·Maurizio GalderisiGiovanni de Simone
Aug 30, 2008·Circulation Journal : Official Journal of the Japanese Circulation Society·Hyungseop KimKwon-Bae Kim
Sep 18, 2013·The International Journal of Cardiovascular Imaging·Cristian MornoşDragoş Cozma
Mar 7, 2014·European Heart Journal Cardiovascular Imaging·Maurizio GalderisiBogdan A Popescu
Jul 6, 2014·Heart Failure Reviews·Mark OremusParminder Raina
Nov 13, 2013·Arquivos brasileiros de cardiologia·Cristian MornosAdina Ionac
Nov 23, 2011·Wiener klinische Wochenschrift·Florian KrackhardtWilhelm Haverkamp
Apr 11, 2009·Heart Failure Reviews·Da-Rong PuQi-chang Zhou
Oct 9, 2012·Journal of Cardiac Failure·Kumudha RamasubbuBiykem Bozkurt
Aug 31, 2011·Progress in Cardiovascular Diseases·Eric Smith Ketchum, Wayne Cecil Levy
Jul 25, 2008·International Journal of Cardiology·Frank Lloyd DiniSalvatore Mario De Tommasi
Feb 22, 2008·The American Journal of Cardiology·Serge Masson, Roberto Latini
Feb 10, 2007·International Journal of Cardiology·Stephane ArquesRoger Luccioni
May 7, 2008·European Journal of Heart Failure·Frank Lloyd DiniSalvatore Mario De Tommasi
Nov 16, 2007·Echocardiography·Bogdan A PopescuGian Luigi Nicolosi
Mar 10, 2010·The American Journal of Cardiology·Simona BuralliStefano Taddei
Aug 6, 2008·The American Journal of Cardiology·Frank Lloyd DiniSalvatore Mario De Tommasi
Jun 1, 2015·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·M A AllisonM Cushman
Jan 7, 2010·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Frank Lloyd DiniVitantonio Di Bello
Feb 20, 2015·European Heart Journal. Acute Cardiovascular Care·Juan LeiKan Liu
Apr 27, 2017·European Heart Journal Cardiovascular Imaging·Patrizio LancellottiBogdan A Popescu
Feb 26, 2020·Journal of cardiology·Stefano NistriAndrea Di Lenarda