Risk stratified breast cancer screening: UK healthcare policy decision-making stakeholders' views on a low-risk breast screening pathway.

BMC Cancer
Lorna McWilliamsDavid P French

Abstract

There is international interest in risk-stratification of breast screening programmes to allow women at higher risk to benefit from more frequent screening and chemoprevention. Risk-stratification also identifies women at low-risk who could be screened less frequently, as the harms of breast screening may outweigh benefits for this group. The present research aimed to elicit the views of national healthcare policy decision-makers regarding implementation of less frequent screening intervals for women at low-risk. Seventeen professionals were purposively recruited to ensure relevant professional group representation directly or indirectly associated with the UK National Screening Committee and National Institute for Health and Care Excellence (NICE) clinical guidelines. Interviews were analysed using thematic analysis. Three themes are reported: (1) producing the evidence defining low-risk, describing requirements preceding implementation; (2) the impact of risk stratification on women is complicated, focusing on gaining acceptability from women; and (3) practically implementing a low-risk pathway, where feasibility questions are highlighted. Overall, national healthcare policy decision-makers appear to believe that risk-stratif...Continue Reading

References

Jul 12, 2002·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·UNKNOWN Breast Screening Frequency Trial Group
Apr 2, 2004·Statistics in Medicine·Jonathan TyrerJack Cuzick
Jul 11, 2009·BMJ : British Medical Journal·Karsten Juhl Jørgensen, Peter C Gøtzsche
Feb 1, 2013·Public Health Genomics·T DentH Burton
Feb 16, 2013·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Susmita ChowdhuryHilary Burton
Jun 8, 2013·British Journal of Cancer·M G MarmotM Wilcox
Oct 12, 2013·CA: a Cancer Journal for Clinicians·Carol DeSantisAhmedin Jemal
Dec 19, 2013·British Journal of Cancer·A J LeeUNKNOWN Breast Cancer Association Consortium
Feb 25, 2015·The Breast : Official Journal of the European Society of Mastology·Susanne F MeiselJane Wardle
Mar 30, 2016·British Journal of Cancer·D Gareth R EvansAnthony Howell
Jul 28, 2016·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Andrew J LeeAntonis C Antoniou
Apr 27, 2017·Breast Cancer Research and Treatment·Jessica A Cintolo-GonzalezKevin S Hughes
Oct 2, 2017·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Ewan GrayKatherine Payne
Mar 13, 2018·The Breast : Official Journal of the European Society of Mastology·Linda RaineyMireille J M Broeders
May 8, 2018·British Journal of Cancer·David P FrenchLouise S Donnelly
Aug 2, 2018·Journal of General Internal Medicine·Xiaofei HeLisa M Schwartz
Feb 26, 2019·The Lancet Oncology·Mary Beth TerryRobert J MacInnis

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Citations

Jul 3, 2021·Journal of Personalized Medicine·Jolyane Blouin-BougieJacques Simard

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