Risks for sensorimotor peripheral neuropathy and autonomic neuropathy in non-insulin-dependent diabetes mellitus (NIDDM)

Muscle & Nerve
J A CohenR W Schrier

Abstract

Identification of risk factors for development of diabetic sensorimotor peripheral neuropathy (DSPN) and diabetic autonomic neuropathy (DNA) may help to prevent or modify these complications. The ABCD Trial, a prospective study of diabetic complications, has identified risk factors of the presence and staging of peripheral neuropathy based on neurological symptom scores, neurological disability scores, autonomic function testing and quantitative sensory examination. DSPN is independently associated with diabetes duration [odds ratio (OR) = 1.5 per 10 years], body weight (OR = 1.1 per 5 kg), age (OR = 1.8 per 10 years), retinopathy (OR = 2.3), overt albuminuria (OR = 2.5), height (OR = 1.2 per 10 cm), duration of hypertension (OR = 1.1 per 10 years), insulin use (OR = 1.4), and race/ethnicity [African American vs. non-Hispanic white (OR = 0.4) and Hispanic vs. non-Hispanic white (OR = 0.8)]. DAN is independently associated with diabetes duration (OR = 1.2 per 10 years), body weight (OR = 1.1 per 5 kg), glycosylated hemoglobin (OR = 1.1 per 2.5%), overt albuminuria (OR = 1.6), and retinopathy (OR = 1.8).

References

Nov 1, 1977·Journal of Neurology, Neurosurgery, and Psychiatry·F BehseF Carlsen
Dec 1, 1992·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·R W Schrier, S Savage
Jan 1, 1990·Journal of Clinical Epidemiology·W R HiattR F Hamman
Jan 1, 1989·Diabetic Medicine : a Journal of the British Diabetic Association·H A NeilJ I Mann
Dec 1, 1986·Diabetes·M W KnuimanI J Constable
May 1, 1969·Circulation·A HaweD C McGoon
Apr 1, 1995·Diabetic Medicine : a Journal of the British Diabetic Association·M D FlynnR J Corrall
Jul 13, 1995·The New England Journal of Medicine·J PartanenM Uusitupa
Jan 1, 1993·Diabetic Medicine : a Journal of the British Diabetic Association·D ZieglerF Lessmann
Sep 30, 1993·The New England Journal of Medicine·UNKNOWN Diabetes Control and Complications Trial Research GroupC Siebert

❮ Previous
Next ❯

Citations

May 13, 2014·Current Neurology and Neuroscience Reports·Gerald A CharnogurskyMary Ann Emanuele
Aug 17, 2012·Expert Review of Cardiovascular Therapy·Georgios KarayannisFilippos Triposkiadis
Mar 10, 2016·Journal of Diabetes Research·Chih-Cheng HuangRue-Tsuan Liu
Sep 29, 2009·Physical Medicine and Rehabilitation Clinics of North America·Karen Wooten
Jul 12, 2008·Pharmacology & Therapeutics·James L EdwardsEva L Feldman
Mar 14, 2016·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Uazman AlamRayaz A Malik
May 20, 2003·Diabetic Medicine : a Journal of the British Diabetic Association·M RahmanN J Wareham
Mar 9, 2006·Muscle & Nerve·T UmapathiYiong Huak Chan
Oct 25, 2013·Diabetic Medicine : a Journal of the British Diabetic Association·A L BarwickV H Chuter
Jan 16, 2007·Muscle & Nerve·T UmapathiYiong Huak Chan
Oct 7, 2011·Diabetes & Metabolism Journal·Jin Ook ChungMin Young Chung
Nov 25, 2003·Diabetes·J Robinson SingletonEva L Feldman
Dec 21, 2006·European Neurology·E A JarmuzewskaA A Mangoni
Nov 1, 2006·International Journal of Clinical Practice·A GirachM Porta
Jun 27, 2006·Journal of Diabetes and Its Complications·Aniz Girach, Louis Vignati
Apr 8, 2017·PloS One·Duck Jin HwangSe Joon Woo
Oct 30, 2008·Diabetes & Vascular Disease Research : Official Journal of the International Society of Diabetes and Vascular Disease·Martin SchönauerHolger Thiele
Jan 17, 2008·American Journal of Alzheimer's Disease and Other Dementias·Behnam SabayanAfshin Borhanihaghighi
Aug 9, 2001·Muscle & Nerve·J W Russell, E L Feldman
Aug 9, 2001·Muscle & Nerve·J R SingletonM B Bromberg
Oct 3, 2017·Continuum : Lifelong Learning in Neurology·Yuebing Li
Jun 20, 2018·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Markus TheurlRudolf Kirchmair
Sep 9, 2006·Current Opinion in Anaesthesiology·Steven H Horowitz
Dec 22, 2004·Current Treatment Options in Neurology·J Robinson SingletonEva L Feldman
Feb 14, 2006·Current Neurology and Neuroscience Reports·Betul M Gundogdu
Mar 1, 2005·The Neurologist·Michael SinnreichP James B Dyck
Jul 27, 2007·Nature Clinical Practice. Nephrology·Robert W SchrierWilliam R Hiatt
Mar 11, 2005·Brain : a Journal of Neurology·Arun V Krishnan, Matthew C Kiernan
Mar 20, 2003·Current Diabetes Reports·A Adler
Apr 16, 2009·Acta Diabetologica·Christian SchaeferNils Hansen-Algenstaedt
Dec 4, 2009·Current Diabetes Reports·Jay M Sosenko
Jul 20, 2012·Continuum : Lifelong Learning in Neurology·A Gordon Smith, J Robinson Singleton
Sep 11, 2010·Journal of Applied Physiology·Zhi Ming, W Wayne Lautt
Apr 23, 2016·Global Heart·Jia ShenNikhil Tandon
Jan 29, 2011·Current Treatment Options in Neurology·Lindsay Zilliox, James W Russell
Apr 30, 2003·Diabetes Care·Aaron I VinikRoy Freeman

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.