PMID: 2490826May 1, 1989Paper

Risks of untreated hypertension. A discussion

Hypertension
L Wilhelmsen

Abstract

There is a strong and graded association between blood pressure and the incidence of major coronary heart disease manifestations, congestive heart failure, stroke, and total mortality. The risk of any of these manifestations is also modified by other risk factors. Tobacco smoking affects the risk for all of the previously mentioned end points. Generally, lipid disturbances are only important predictors of coronary heart disease and total mortality. Several facts indicate that elevated blood pressure is causally related to the end points. There are, however, positive relations between blood pressure levels and heart rate, serum cholesterol level, body mass index, and, according to some studies, glucose intolerance. Some more basic abnormality may be responsible for the blood pressure increase and the increases in these other factors. Hypothetically, this abnormality may be more fundamentally related to some of the end points than is hypertension itself. If that is the case, then the type of antihypertensive treatment may be of decisive importance. Different end points may be affected differently by antihypertensive drugs, a factor that may be essential in the choice of drug treatment. Proper management of other risk factors is a...Continue Reading

References

Dec 1, 1978·Clinical Science and Molecular Medicine. Supplement·D G BeeversD M Titterington
Jan 1, 1976·Acta Medica Scandinavica·G BerglundL Wilhelmsen
Aug 6, 1987·The New England Journal of Medicine·E FerranniniS Bevilacqua
Nov 1, 1984·Hypertension·L Wilhelmsen
Aug 23, 1984·The New England Journal of Medicine·L WilhelmsenG Tibblin

❮ Previous
Next ❯

Citations

Jan 7, 1999·Journal of Diabetes and Its Complications·W V MooreR Guthrie
Jul 17, 2003·Kidney International. Supplement·Agnes B Fogo
Oct 1, 1995·Journal of the American College of Nutrition·F J Haddy, M B Pamnani
Mar 1, 1996·Ethnicity & Health·G S TellJ Burkart
Dec 19, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C HadiganS Grinspoon
Jan 20, 2007·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Gösta FlorvallAnders Larsson
Feb 10, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Luis M Ruilope
Apr 9, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·R VanholderUNKNOWN European Uremic Toxin Work Group
Jul 21, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Matthew R Weir
Nov 26, 2008·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Kaivan KhavandiAnthony M Heagerty
Apr 17, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Niina KoivuviitaKaj Metsärinne
May 1, 1996·Journal of Cardiovascular Pharmacology·S SunanoK Shimamura
Jul 24, 1998·Journal of Cardiovascular Pharmacology·N M GenevD K Yue
Feb 24, 1999·Journal of Cardiovascular Pharmacology·A Zanchetti, A Stella
Feb 24, 1999·Journal of Cardiovascular Pharmacology·L M Ruilope
Jul 20, 2002·The Nurse Practitioner·Helen Q Reynolds, Prakash C Deedwania
May 1, 2002·Current Opinion in Nephrology and Hypertension·Chi-Yuan Hsu
Jul 1, 2006·Blood Pressure Monitoring·Dogan ErdoganHaldun Muderrisoglu
Jan 7, 2010·Current Opinion in Nephrology and Hypertension·Mariana Murea, Barry I Freedman
Apr 11, 2012·Current Opinion in Nephrology and Hypertension·Tamara Isakova
May 15, 2007·Current Opinion in Pediatrics·Mouin G Seikaly
Oct 16, 2004·Kidney International. Supplement·Julian SeguraLuis M Ruilope
Jan 19, 2008·Artificial Organs·Robert EkartBreda Pecovnik Balon
Jun 1, 1997·Canadian Journal of Physiology and Pharmacology·J ChaoL Chao
Feb 27, 2007·Vascular Health and Risk Management·Helen A LaneJ Stephen Davies
Sep 15, 2004·PharmacoEconomics·Luca Degli Esposti, Giorgia Valpiani
Feb 24, 2005·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Jean-Philippe BaguetPascal Auquier
Aug 21, 2013·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·André MierschWieland Kiess
Jul 23, 2013·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·André MierschWieland Kiess
May 21, 2015·Current Diabetes Reports·Mark Henry Joven, Robert J Anderson

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.