Rituximab: a novel treatment for refractory Riedel's thyroiditis

Endocrinology, Diabetes & Metabolism Case Reports
Leanne HuntAmit Allahabadia

Abstract

This case report reviews the rare condition of Riedel's thyroiditis via a patient case. The report highlights the difficulties that one may encounter when managing such a case in regards to patient symptoms, side effects of medications and the relapsing nature of the condition. The case report also highlights novel treatment in the treatment of Riedel's thyroiditis, rituximab, how this works and the resolution of symptoms that we have achieved with our patient on this treatment. Riedel's thyroiditis is characterised by chronic inflammation, which causes dense fibrosis in the thyroid gland.Riedel's thyroiditis can present with neck pain, dysphagia and dyspnoea with a firm, non-tender mass found on examination.Riedel's thyroiditis is part of the IgG4-related systemic disorders.Rituximab is a monoclonal antibody that works against the protein CD20.

References

Dec 1, 1988·American Journal of Clinical Pathology·S M SchwaegerleC B Esselstyn
Dec 1, 1985·Mayo Clinic Proceedings·I D Hay
Apr 1, 1995·Journal of Endocrinological Investigation·M BagnascoA Scordamaglia
Mar 1, 1994·Journal of Internal Medicine·T Zimmermann-Belsing, U Feldt-Rasmussen
Mar 14, 1998·Postgraduate Medical Journal·B VaidyaP Kendall-Taylor
Apr 27, 2002·European Radiology·Kader Karli OguzAytac Gokoz
Feb 1, 1957·The Journal of Clinical Endocrinology and Metabolism·O H BEAHRSL B WOOLNER
Jul 13, 2004·European Journal of Internal Medicine·Pirkko KotilainenPirjo Nuutila
Aug 8, 2006·Thyroid : Official Journal of the American Thyroid Association·Daniel El FassiLaszlo Hegedüs
Jan 29, 2008·Gastroenterology·Amaar GhazaleMichael B Farnell
Jul 17, 2008·European Journal of Endocrinology·Karen A HeemstraJohannes W Smit
Jul 29, 2009·Archives of Dermatological Research·Alfredo GragnaniLydia Masako Ferreira
Jan 14, 2010·Thyroid : Official Journal of the American Thyroid Association·Joshua M LevyMarc J Kahn
Aug 25, 2010·Advances in Anatomic Pathology·Wah Cheuk, John K C Chan
Dec 3, 2010·Current Opinion in Rheumatology·Arezou Khosroshahi, John H Stone
May 17, 2011·Thyroid : Official Journal of the American Thyroid Association·Mitra M FatourechiVahab Fatourechi
Aug 13, 2011·The Journal of Clinical Endocrinology and Metabolism·James V Hennessey
Feb 10, 2012·The New England Journal of Medicine·John H StoneVikram Deshpande
Jul 5, 2013·The Journal of Clinical Endocrinology and Metabolism·Shui-Boon SohDuncan J Topliss

❮ Previous
Next ❯

Citations

Jul 21, 2020·The Journal of Clinical Endocrinology and Metabolism·Aakansha ZalaHenrik Falhammar

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Medicina clínica
Geraldine López-Sánchez, Eduardo Reyna-Villasmil
Revue de laryngologie - otologie - rhinologie
P RogerA Valdazo
Anales españoles de pediatría
M D Rodríguez SánchezL Lorenzo Navarro
Endocrinologia e scienza della costituzione
G DELAINI
© 2022 Meta ULC. All rights reserved