Rituximab and intravenous immunoglobulins for relapsing postinfectious opsoclonus-myoclonus syndrome

Pediatric Neurology
Wilhelmina G LeenJan J Rotteveel

Abstract

We describe 2 children with postinfectious opsoclonus-myoclonus syndrome. Although the patients initially responded to monotherapy with methylprednisolone, intravenous immunoglobulins, or rituximab, they manifested persistent neurologic deficits and relapsing signs. Treatment with rituximab in combination with intravenous immunoglobulin, however, resulted in significant longterm clinical improvement.

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Dec 2, 2010·Clinical Rheumatology·Annette F JanssonVeit Grote
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Jul 3, 2021·Journal of Clinical Medicine·Giacomo GaroneAlessandro Capuano

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