RNA and DNA microarrays

Methods in Molecular Biology
Stuart C Sealfon, Tearina T Chu

Abstract

The development of microarray technology has revolutionized RNA and deoxyribonucleic acid (DNA) research. In contrast with traditional biological assays, microarrays allow the simultaneous measurement of tens of thousands of messenger RNA (mRNA) transcripts for gene expression or of genomic DNA fragments for copy number variation analysis. Over the past decade, genome-wide RNA or DNA microarray analysis has become an essential component of biology and biomedical research. The successful use of microarrays requires attention to unique issues of experimental design and execution. This chapter provides an overview of the methodology and applications of RNA and DNA microarrays in various areas of biological research.

Citations

Nov 14, 2014·Journal of Cellular Physiology·Alzenira Costa, Octavio Luiz Franco
Apr 21, 2019·Pharmaceutical Research·Cameron L NemethTejal A Desai
Apr 11, 2019·Frontiers in Oncology·Quan ZhouMan-Zhen Zuo
Jul 13, 2020·Trends in Biotechnology·Samara Martín-AlonsoLuis Menéndez-Arias
Jan 29, 2021·Expert Review of Anticancer Therapy·María Gallardo-GómezJoaquin Cubiella
Dec 15, 2020·Open Medicine·Yanbo DongLiangfa Liu

Related Concepts

Metazoa
DNA, Double-Stranded
RNA
cDNA Probes
Cdna Microarrays
MRNA Differential Display
Bacterial Artificial Chromosomes
Array-Based Comparative Genomic Hybridization
Biomedical Research
DNA

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