PMID: 7540936Feb 1, 1995Paper

RNA-d2: a computer program for editing and display of RNA secondary structures

Computer Applications in the Biosciences : CABIOS
J Perochon-DorisseB Michot

Abstract

RNA-d2 is a user-friendly program developed for interactively generating aesthetic and non-overlapping drawings of RNA secondary structures. It designed so that the drawings can be edited in a very natural and intuitive way, in order to emphasize structural homologies between several molecules, as well as the foldings themselves to update the base-pair sets according to new data. The program automatically produces a polygonal display in which the unpaired nucleotides are regularly positioned on circles and the stems harmoniously distributed on their periphery. RNA secondary structures can be encoded via the keyboard, but the program also automatically draws output files from thermodynamic prediction programs. The user interacts directly on different screen displays according to the editing functions. Rotation/translation of any subdomain and deletion of stems are performed on a coloured backbone view to make easier the identification of structural features, whereas addition of new base-pairings and numbering manipulation are realized on a complete polygonal view. Each modification is displayed in real time on the screen. When the display is obscured by numerous overlaps despite the colour code of the backbone view, an automatic...Continue Reading

Citations

Aug 1, 1996·Histochemistry and Cell Biology·M F TrendelenburgH Spring
Apr 1, 2009·Briefings in Bioinformatics·Peng Zhou, Zhicai Shang
Aug 25, 1995·Nucleic Acids Research·B SchmidH U Göringer
Apr 24, 1996·Molecular & General Genetics : MGG·L OttenB Michot
Oct 1, 1997·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·L Selakovitch-ChenuM Sicard

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