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RNA interference inhibits hepatitis B virus gene expression and replication in HepG2-N10 cells

Chinese Journal of Digestive Diseases

Oct 24, 2006

Jian Lin RenYa Mei Lian

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Abstract

RNA interference (RNAi) refers to the phenomenon of sequence-specific degradation of homologous mRNA induced by double-stranded RNA. It has been successfully utilized to down-regulate endogenous gene expression or suppress the replication of various pathogens in mammalian cells. In this...read more

Mentioned in this Paper

Real-Time Polymerase Chain Reaction
Shuttle Vectors
Covalent Interaction
Hepatitis Be Antigen Measurement
Transfection
HBe Ag-2
RNA, Small Interfering
Cosuppression
RNA, Double-Stranded
Hepatitis B e Antigens
Paper Details
References
  • References29
  • Citations4
123
  • References29
  • Citations4
1

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RNA interference inhibits hepatitis B virus gene expression and replication in HepG2-N10 cells

Chinese Journal of Digestive Diseases

Oct 24, 2006

Jian Lin RenYa Mei Lian

PMID: 17054586

DOI: 10.1111/j.1443-9573.2006.00268.x

Abstract

RNA interference (RNAi) refers to the phenomenon of sequence-specific degradation of homologous mRNA induced by double-stranded RNA. It has been successfully utilized to down-regulate endogenous gene expression or suppress the replication of various pathogens in mammalian cells. In this...read more

Mentioned in this Paper

Real-Time Polymerase Chain Reaction
Shuttle Vectors
Covalent Interaction
Hepatitis Be Antigen Measurement
Transfection
HBe Ag-2
RNA, Small Interfering
Cosuppression
RNA, Double-Stranded
Hepatitis B e Antigens

Feeds With Similar Papers

RNAi & Gene Silencing

RNA Interference (RNAi) pathway is involved in post-transcriptional gene silencing, transcriptional silencing and epigenetic silencing as well as its use as a tool for forward genetics and therapeutics. Discover the latest research here.

Related Papers

World Journal of Gastroenterology : WJG

siRNA-mediated inhibition of HBV replication and expression

World Journal of Gastroenterology : WJGSeptember 21, 2004
Xiao-Nan ZhangZheng-Hong Yuan
Paper Details
References
  • References29
  • Citations4
123
  • References29
  • Citations4
1

Download from

Publisher
PubMed
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