Aug 14, 2014

RNA-Rocket: An RNA-Seq Analysis Resource for Infectious Disease Research

bioRxiv
Andrew S. WarrenBruno Sobral

Abstract

Motivation RNA-Seq is a method for profiling transcription using high-throughput sequencing and is an important component of many research projects that wish to study transcript isoforms, condition specific expression, and transcriptional structure. The methods, tools, and technologies employed to perform RNA-Seq analysis continue to change, creating a bioinformatics challenge for researchers who wish to exploit these data. Resources that bring together genomic data, analysis tools, educational material, and computational infrastructure can minimize the overhead required of life science researchers. Results RNA-Rocket is a free service that provides access to RNA-Seq and ChIP-Seq analysis tools for studying infectious diseases. The site makes available thousands of pre-indexed genomes, their annotations, and the ability to stream results to the bioinformatics resources VectorBase, EuPathDB, and PATRIC. The site also provides a combination of experimental data and metadata, examples of pre-computed analysis, step-by-step guides, and a user interface designed to enable both novice and experienced users of RNA-Seq data. Availability RNA-Rocket can be found at [rnaseq.pathogenportal.org][1] Source code for this project can be fou...Continue Reading

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Mentioned in this Paper

Research
Environmental Infrastructure
Genome
Transcription, Genetic
Research Personnel
Bio-Informatics
Site
Genomics
Sequencing
Sequence Analysis, RNA

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