Roadmap for the international collaborative epidemiologic monitoring of safety and effectiveness of new high priority vaccines

Vaccine
Hector IzurietaSteve Black

Abstract

With the advent of new vaccines targeted to highly endemic diseases in low- and middle-income countries (LMIC) and with the expansion of vaccine manufacturing globally, there is an urgent need to establish an infrastructure to evaluate the benefit-risk profiles of vaccines in LMIC. Fortunately the usual decade(s)-long time gap between introduction of new vaccines in high and low income countries is being significantly reduced or eliminated due to initiatives such as the Global Alliance for Vaccines and Immunizations (GAVI) and the Decade of Vaccines for the implementation of the Global Vaccine Action Plan. While hoping for more rapid disease control, this time shift may potentially add risk, unless appropriate capacity for reliable and timely evaluation of vaccine benefit-risk profiles in some LMIC's are developed with external assistance from regional or global level. An ideal vaccine safety and effectiveness monitoring system should be flexible and sustainable, able to quickly detect possible vaccine-associated events, distinguish them from programmatic errors, reliably and quickly evaluate the suspected event and its association with vaccination and, if associated, determine the benefit-risk of vaccines to inform appropriate...Continue Reading

References

Apr 9, 2004·The Pediatric Infectious Disease Journal·Frederick VarricchioRobert T Chen
Oct 13, 2005·Statistics in Medicine·Heather J WhitakerPatrick Musonda
Feb 7, 2008·Expert Review of Vaccines·Steven Black
Jul 25, 2008·Archives of Disease in Childhood·K SextonR Drake
Jul 1, 2009·Tropical Medicine & International Health : TM & IH·Sitaporn YoungkongRob Baltussen
Oct 30, 2009·Expert Review of Vaccines·Manish M PatelUmesh D Parashar
Dec 8, 2009·Nature Reviews. Microbiology·Simon J Draper, Jonathan L Heeney
Jun 17, 2011·The New England Journal of Medicine·Manish M PatelUmesh D Parashar
Apr 18, 2012·Vaccine·Bruce Aylward, Rudolf Tangermann
Jul 17, 2012·International Journal of Epidemiology·Osman Sankoh, Peter Byass
Feb 1, 2012·Therapeutic Advances in Drug Safety·Gordon Mallarkey, Arduino A Mangoni

Citations

Apr 1, 2014·Travel Medicine and Infectious Disease·Sandra Köhli Weber, Patricia Schlagenhauf
Oct 5, 2015·Vaccine·Robert T ChenMiriam Sturkenboom
Nov 23, 2015·American Journal of Preventive Medicine·Robert T ChenMiriam Sturkenboom
Nov 29, 2016·Pharmacoepidemiology and Drug Safety·Wan-Ting HuangPhilip H Rhodes
Jan 29, 2019·Expert Review of Vaccines·Adrienne GuignardLaurence Baril
May 4, 2017·Human Vaccines & Immunotherapeutics·Gayathri SridharHector Izurieta
Jun 20, 2020·Nature Reviews. Immunology·Rebecca E Chandler

Related Concepts

Parasite Control
Communicable Diseases
Vaccination
Vaccines
Benefit-Risk Assessment
Epidemiological Monitoring
Cell Growth
Immunization
Meningococcal Infections
Oculocerebrorenal Syndrome

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