PMID: 6404548May 1, 1983Paper

Robertsonian translocation studies on the significance of trisomy 15 in murine T-cell leukemia

Cancer Genetics and Cytogenetics
J SpiraG Klein

Abstract

G-banding analysis was carried out on T-cell leukemias induced in various Robertsonian mice by 7,12 dimethylbenz(a)anthracene (DMBA), N-methyl-N-nitrosourea (MNU), or Moloney virus. Trisomy 15 was the only regularly seen chromosome aberration whether chromosome No. 15 was involved in a centric fusion or not. Translocated No. 15 chromosomes were not preferentially duplicated. These results show that it is not the translocated state of chromosome No. 15 but the genetic content that is of importance in leukemia development.

References

Oct 15, 1978·International Journal of Cancer. Journal International Du Cancer·F WienerG Klein
Apr 15, 1979·International Journal of Cancer. Journal International Du Cancer·F WienerG Klein
Dec 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·J SpiraG Klein
Apr 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·R DofukuL J Old
Jan 12, 1972·Nature: New Biology·H C Wang, S Fedoroff
Nov 15, 1980·International Journal of Cancer. Journal International Du Cancer·F WienerG Klein

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Citations

Sep 1, 1987·Cancer Genetics and Cytogenetics·D AubertR Berger
Oct 24, 2001·Cancer Genetics and Cytogenetics·V FabrisS Merani
Oct 2, 2001·Archives of Medical Research·C Orozco-BuenrostroC M Torres
Sep 6, 2003·Free Radical Biology & Medicine·Toby N Behar, Carol A Colton
Sep 7, 2006·Cytogenetic and Genome Research·C RudolphB Schlegelberger
May 15, 1988·International Journal of Cancer. Journal International Du Cancer·S SilvaG Klein
Apr 2, 2010·QJM : Monthly Journal of the Association of Physicians·G LiamisM Elisaf

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