Abstract
To evaluate the survival outcomes of consecutive patients with locally advanced cervical cancer (LACC) who underwent comprehensive robotic surgery after neoadjuvant chemotherapy (NACT). Since 2009, patients with LACC (FIGO [International Federation of Gynecology and Obstetrics] stages IB2-IIB) were submitted to robotic surgical staging after 3 cycles of NACT. Clinical objective tumor response was assessed according to the Response Evaluation Criteria in Solid Tumors, whereas pathologic responses were defined according to the criteria of the European study SNAP01. Univariable and multivariable analyses were performed to assess potential clinicopathologic prognostic factors affecting progression-free survival and overall survival (OS). During the study period, 32 patients meeting the inclusion criteria were managed. The median (range) age and body mass index were 47.3 (8.6-75.5) years and 22.7 (17.5-37.1) kg/m(2), respectively. Overall, 28.0 (range, 12-58) lymph nodes were retrieved. According to the final pathologic examination, 6 (18.8%) women had positive pelvic lymph nodes, whereas 16 (50.0%) patients achieved an optimal pathological response. After a median follow-up of 36.3 (range, 5.2-71.1) months, 6 (18.8%) patients had a...Continue Reading
References
Nov 5, 1997·Gynecologic Oncology·J E SardiG di Paola
Dec 24, 1997·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A LissoniC Sessa
Nov 18, 1998·Annals of Oncology : Official Journal of the European Society for Medical Oncology·G ZanettaC Mangioni
Mar 30, 1999·Gynecologic Oncology·P MoriceP Duvillard
Jun 18, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Alessandro BudaCostantino Mangioni
Jun 13, 2006·The Journal of Obstetrics and Gynaecology Research·Hong-Bing CaiHou-Han Yin
Dec 13, 2006·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·M A QuinnS Pecorelli
May 12, 2007·Gynecologic Oncology·Gary L EddyDennis O'Connor
Aug 31, 2007·Gynecologic Oncology·Pieluigi Benedetti PaniciRoberto Angioli
Mar 1, 2008·The Lancet Oncology·Denis Querleu, C Paul Morrow
Nov 13, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·UNKNOWN Chemoradiotherapy for Cervical Cancer Meta-Analysis Collaboration
Dec 23, 2008·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·E A EisenhauerJ Verweij
Feb 3, 2009·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A A LissoniE Rulli
Apr 16, 2009·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Sergio Pecorelli
May 28, 2009·Journal of Gynecologic Oncology·Yun-Hyun ChoJoo-Hyun Nam
Jun 27, 2009·Gynecologic Oncology·P E ColomboP Rouanet
Mar 20, 2012·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·D VitobelloN Iedà
Jun 26, 2012·Gynecologic Oncology·Seiji MabuchiTadashi Kimura
Jul 24, 2012·Gynecologic Oncology·Roberto AngioliPierluigi Benedetti-Panici
Nov 6, 2012·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·D VitobelloN Ieda
Dec 12, 2012·Annals of Surgical Oncology·Fabio GhezziMassimo Franchi
Dec 15, 2012·Gynecologic Oncology·G FerrandinaG Scambia
Mar 5, 2013·Gynecologic Oncology·Gabriele SiestoDomenico Vitobello
Mar 5, 2014·Gynecologic Oncology·Enrico VizzaAngelo Maggioni
Apr 17, 2014·BJOG : an International Journal of Obstetrics and Gynaecology·J P HoogendamR P Zweemer
Nov 1, 2006·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·M A QuinnS Pecorelli