Robust Q-learning.

Journal of the American Statistical Association
Ashkan ErtefaieRobert L Strawderman

Abstract

Q-learning is a regression-based approach that is widely used to formalize the development of an optimal dynamic treatment strategy. Finite dimensional working models are typically used to estimate certain nuisance parameters, and misspecification of these working models can result in residual confounding and/or efficiency loss. We propose a robust Q-learning approach which allows estimating such nuisance parameters using data-adaptive techniques. We study the asymptotic behavior of our estimators and provide simulation studies that highlight the need for and usefulness of the proposed method in practice. We use the data from the "Extending Treatment Effectiveness of Naltrexone" multi-stage randomized trial to illustrate our proposed methods.

References

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Methods Mentioned

BETA
GAM-GAM

Software Mentioned

dWLOS
SuperLearner
InterQuad
randomForest
FGS
R package
ExTENd
dWOLS
Linear
Super Learner

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