journal cover

Robustness and evolvability in genetic regulatory networks

Journal of Theoretical Biology

Dec 26, 2006

Maximino AldanaOsbaldo Resendiz

Download from

Publisher
PubMed

Abstract

Living organisms are robust to a great variety of genetic changes. Gene regulation networks and metabolic pathways self-organize and reaccommodate to make the organism perform with stability and reliability under many point mutations, gene duplications and gene deletions. At the same ti...read more

Mentioned in this Paper

Biochemical Pathway
Conserved Sequence
Caenorhabditis elegans
Espinosa
Transcription, Genetic
Contraction (Finding)
Gene Deletion
Gene Expression
Cell Differentiation Process
Genes, Regulator
253
1
Paper Details
References
  • References41
  • Citations91
12345
  • References41
  • Citations91
12345...

Feeds With Similar Papers

Conserved Gene Regulation (Keystone)

Conserved gene regulation are specific regulatory elements of the genome that are evolutionarily conserved. These elements include topologically associating domains (TADs) and cis-regulatory elements (CREs) and have specific roles in the genomic coding function. Find the latest research on FGF8 Locus Split-Hand/Foot Malformation Type 3here.

Chromosomal Duplication

Chromosomal duplication is a result of extra genetic material within the area of the chromosome. The duplication may have no effect or may be expressed in the phenotype of that individual. Some duplications are thought to be of evolutionary selection. Discover the latest research on chromosomal duplication here.

Conserved Gene Regulation and CTCFL (Keystone)

Conserved gene regulation refers to regulatory elements of the genome that are evolutionarily conserved. CTCFL is a specific element that plays a part in X-chromosome inactivation. It is thought to be incorrectly activated in some cancers. Find the latest research on conserved gene regulation and CTCFL here.

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

Conserved Gene Regulation

Conserved gene regulation refers to regulatory elements of the genome that are evolutionarily conserved. These elements include topologically associating domains (TADs) and cis-regulatory elements (CREs). Find the latest research on conserved gene regulation here.

Related Papers

PLoS Computational Biology

Robustness can evolve gradually in complex regulatory gene networks with varying topology

PLoS Computational BiologyFebruary 6, 2007
S CilibertiAndreas Wagner
Proceedings of the National Academy of Sciences of the United States of America

Innovation and robustness in complex regulatory gene networks

Proceedings of the National Academy of Sciences of the United States of AmericaAugust 11, 2007
S CilibertiAndreas Wagner
© 2020 Meta ULC. All rights reserved

Robustness and evolvability in genetic regulatory networks

Journal of Theoretical Biology

Dec 26, 2006

Maximino AldanaOsbaldo Resendiz

PMID: 17188715

DOI: 10.1016/j.jtbi.2006.10.027

Abstract

Living organisms are robust to a great variety of genetic changes. Gene regulation networks and metabolic pathways self-organize and reaccommodate to make the organism perform with stability and reliability under many point mutations, gene duplications and gene deletions. At the same ti...read more

Mentioned in this Paper

Biochemical Pathway
Conserved Sequence
Caenorhabditis elegans
Espinosa
Transcription, Genetic
Contraction (Finding)
Gene Deletion
Gene Expression
Cell Differentiation Process
Genes, Regulator
253
1

Feeds With Similar Papers

Conserved Gene Regulation (Keystone)

Conserved gene regulation are specific regulatory elements of the genome that are evolutionarily conserved. These elements include topologically associating domains (TADs) and cis-regulatory elements (CREs) and have specific roles in the genomic coding function. Find the latest research on FGF8 Locus Split-Hand/Foot Malformation Type 3here.

Chromosomal Duplication

Chromosomal duplication is a result of extra genetic material within the area of the chromosome. The duplication may have no effect or may be expressed in the phenotype of that individual. Some duplications are thought to be of evolutionary selection. Discover the latest research on chromosomal duplication here.

Related Papers

PLoS Computational Biology

Robustness can evolve gradually in complex regulatory gene networks with varying topology

PLoS Computational BiologyFebruary 6, 2007
S CilibertiAndreas Wagner
Proceedings of the National Academy of Sciences of the United States of America

Innovation and robustness in complex regulatory gene networks

Proceedings of the National Academy of Sciences of the United States of AmericaAugust 11, 2007
S CilibertiAndreas Wagner
Paper Details
References
  • References41
  • Citations91
12345
  • References41
  • Citations91
12345...

Download from

Publisher
PubMed
/papers/robustness-and-evolvability-in-genetic-regulatory/17188715