Role of a cefoxitin-inducible beta-lactamase in a case of breakthrough bacteremia.

Journal of Clinical Microbiology
D G Beckwith, J A Jahre

Abstract

Development of resistance during therapy with cefamandole contributes to treatment failure. A simple cefoxitin disk test was recently described which detects a cefamandole-active inducible beta-lactamase not otherwise detectable with cefamandole as the inducer. A case of breakthrough Enterobacter bacteremia due to selection of a resistant subpopulation is reported in an immunocompromised patient. The use of this simple disk test in selected clinical cases is advocated.

References

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Citations

Aug 1, 1989·Antimicrobial Agents and Chemotherapy·T GootzS Sokolowski
Jun 1, 1982·Antimicrobial Agents and Chemotherapy·R V GoeringW E Sanders
May 1, 1984·Antimicrobial Agents and Chemotherapy·T D GootzJ C Sherris
Mar 1, 1989·Journal of Clinical Microbiology·M A GastonT L Pitt
Jul 1, 1983·Antimicrobial Agents and Chemotherapy·C C SandersR V Goering
Oct 1, 1984·Antimicrobial Agents and Chemotherapy·A J Godfrey, L E Bryan
Feb 1, 1983·Journal of Clinical Microbiology·A L BarryC Thornsberry

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