PMID: 2101Jan 1, 1975

Role of acetate metabolism in sporulation of Saccharomyces carlsbergensis

Antonie van Leeuwenhoek
C P Görts

Abstract

Several aspects of the role of acetate metabolism in the sporulation of Saccaromyces carlsbergensis were investigated. Experiments in which the development of the respiratory system was either stimulated by growth on sugars to which the cells have to adapt, or inhibited by chloramphenicol suggested a correlation between respiratory development and sporulation. In cells in which the respiratory system has been repressed during growth, mitobhondrial protein synthesis and derepression are prerequisites for sporulation. When derepression is complete, sporulation no longer depends on mitochondrial protein synthesis. Incorporation experiments with acetate showed that this compound is an important source of intermediates for biosynthetic processes that occur during sporulation. Its incorporation into macromolecular fractions is tightly coupled to sporutlation.

Citations

Jul 22, 1998·Molecular and Cellular Biology·S M Honigberg, R H Lee

Related Concepts

Acetic Acids
Syntomycin
Deoxyglucose
Hydrogen-Ion Concentration
Mitochondria
Reproduction
Reproduction, Asexual
Saccharomyces
Conidia

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