Oct 1, 1987

Role of Amino Acids and Vitamins in Nutrition of Mesophilic Methanococcus spp

Applied and Environmental Microbiology
W B WhitmanR Y Xing

Abstract

In this study we found that autotrophic methanococci similar to Methanococcus maripaludis obtained up to 57% of their cellular carbon from exogenous amino acids. About 85% of the incorporation was into protein. Primarily nonpolar and basic amino acids and glycine were incorporated; only small amounts of acidic and some polar amino acids were taken up. An additional 10% of the incorporation was into the nucleic acid fraction. Because little CO(2) was formed from the C-amino acids, little metabolism of the amino acids occurred. Therefore the growth stimulation by amino acids was probably due to the sparing of anabolic energy requirements. Of the amino acids incorporated, only alanine was also a sole nitrogen source for these methanococci. In contrast, Methanococcus vannielii and "Methanococcus aeolicus" are autotrophic methanococci which did not incorporate amino acids and did not utilize alanine as a sole nitrogen source. Although glutamine served as a sole nitrogen source for the autotrophic methanococci and Methanococcus voltae, a heterotrophic methanococcus, growth was due to chemical deamination in the medium. M. voltae requires leucine and isoleucine for growth. However, these amino acids were not significant nitrogen sourc...Continue Reading

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Mentioned in this Paper

Metabolic Process, Cellular
Methanococcus maripaludis
Amino Acids, I.V. solution additive
Methanococcus
Catabolic Process
Glycine
Glycine (Plant)
Methanococcus voltae
Metabolic Pathway
Isoleucine Measurement

About this Paper

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