Role of apoptosis in common variable immunodeficiency and selective immunoglobulin A deficiency

Molecular Immunology
Reza YazdaniAsghar Aghamohammadi

Abstract

Common variable immunodeficiency (CVID) and selective IgA deficiency (SIgAD) are the most common primary immunodeficiencies in human. Both diseases share clinical manifestation and molecular defects. Increased apoptosis may be one of the mechanisms involved in the pathogenesis of CVID and SIgAD. Elevated apoptosis in this disorder leads to defective long-term survival of B-cells, reduced antibody production, decreased lymphocyte proliferation and defective cytokine secretion. For the first time, we reviewed the role of apoptosis in CVID and SIgAD.

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Citations

Sep 12, 2016·Cellular Immunology·Gholamreza AziziAsghar Aghamohammadi
Sep 17, 2016·Expert Review of Clinical Immunology·Gholamreza AziziAsghar Aghamohammadi
Sep 25, 2016·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Reza YazdaniAsghar Aghamohammadi
Oct 21, 2016·Scandinavian Journal of Immunology·R YazdaniA Aghamohammadi
Nov 20, 2016·Scandinavian Journal of Immunology·G AziziA Aghamohammadi
Dec 26, 2016·International Archives of Allergy and Immunology·Gholamreza AziziAsghar Aghamohammadi
Jul 4, 2019·Clinical Reviews in Allergy & Immunology·David D Odineal, M Eric Gershwin
Dec 21, 2018·Journal of Clinical Immunology·Dina M AresvikTore G Abrahamsen
Jul 29, 2020·International Journal of Molecular Sciences·Ida Judyta MaleszaPiotr Eder
Apr 17, 2017·Allergologia et immunopathologia·A Tak ManeshA Aghamohammadi
Dec 7, 2018·Allergologia et immunopathologia·S Afshar-GhasemlouA Rezaei
Apr 29, 2018·Allergologia et immunopathologia·R YazdaniN Rezaei
Aug 26, 2021·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Weiling LengQinan Wu
May 16, 2019·International Archives of Allergy and Immunology·Yasser BagheriAsghar Aghamohammadi

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