Abstract
Oral cancer appears to be increasing in incidence, and mortality has hardly improved over the past 25 years. Better understanding of the etiopathogenesis should lead to more accurate and earlier diagnosis and more effective treatments with fewer adverse effects. Despite increasing interest in the possible relationships between bacteria and the different stages of cancer development, the association of bacteria with cancer of the oral cavity has yet to be adequately examined. Different bacteria have been proposed to induce carcinogenesis, either through induction of chronic inflammation or by interference, either directly or indirectly, with eukaryotic cell cycle and signaling pathways or by metabolism of potentially carcinogenic substances like acetaldehyde, causing mutagenesis. This review presents the possible carcinogenesis pathway involved in bacterial carcinogenesis, commonly implicated bacteria in oral carcinogenesis and their role in cancer therapeutics as well.
References
Jun 1, 1985·Carcinogenesis·S CalmelsH Bartsch
Jun 1, 1974·Transactions of the New York Academy of Sciences·V W Livingston, A M Livingston
Nov 1, 1995·Environmental Health Perspectives·J Parsonnet
Nov 14, 1998·Oral Oncology·K N NagyH N Newman
Oct 13, 2000·Science·M Lara-Tejero, J E Galán
Mar 7, 2002·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·H KoyiB Steen
Jun 29, 2002·Trends in Microbiology·Alistair J Lax, Warren Thomas
May 21, 2003·Critical Reviews in Clinical Laboratory Sciences·Mikko P Salaspuro
Mar 2, 2005·Trends in Microbiology·Jean-Philippe NougayrèdeEric Oswald
Apr 5, 2005·Nature Reviews. Microbiology·Alistair J Lax
May 13, 2005·Oral Diseases·M SasakiS Kimura
May 5, 2006·Journal of Clinical Microbiology·Samuel J HooperMelanie J Wilson
Nov 24, 2007·Journal of Medical Microbiology·Samuel J HooperMelanie J Wilson
Jun 26, 2009·Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research·R RajendranAbdul Gafoor Rabi
Sep 24, 2009·BMC Oral Health·Neluka FernandoJohn Holton
Oct 12, 2010·Clinical Microbiology Reviews·Alicia H Chang, Julie Parsonnet
Jan 6, 2011·FEMS Immunology and Medical Microbiology·Smruti PushalkarDeepak Saxena
May 18, 2011·Indian Journal of Medical and Paediatric Oncology : Official Journal of Indian Society of Medical & Paediatric Oncology·Noureen ChocolatewalaRushikesh Desale
May 24, 2011·Annals of Clinical Microbiology and Antimicrobials·Manju PanghalJaya P Yadav
Jul 24, 2012·BMC Microbiology·Smruti PushalkarDeepak Saxena
Jun 25, 2013·Clinical Oral Investigations·J BolzA W Eckert
Oct 1, 2013·Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission·R MetgudJ Gupta
Oct 1, 2012·South Asian Journal of Cancer·R RajeevNeha Gandhi
Citations
Sep 8, 2016·Journal of Oral and Maxillofacial Pathology : JOMFP·Radhika Manoj Bavle, Sreelatha S Hosthor
Nov 15, 2018·Carcinogenesis·Mohd Hafiz ArzmiMichael McCullough
Jun 12, 2019·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Mohd Hafiz ArzmiMichael McCullough
Feb 6, 2020·Frontiers in Cellular and Infection Microbiology·Ling ZhangChen Ping Zhang
Sep 22, 2019·Experimental Cell Research·Wei-Long ZhangXin-Hua Liang
Jan 19, 2021·Journal of Oral and Maxillofacial Pathology : JOMFP·Priya Nimish Deo, Revati Deshmukh