Role of bovine herpesvirus 4 in bacterial bovine mastitis

Microbial Pathogenesis
D KálmánL Egyed

Abstract

In order to study the role played by bovine herpesvirus 4 (BoHV-4) in bovine mastitis, PCR experiments were performed on a Hungarian dairy herd of 2000 cows. Milk cells were tested with a nested PCR adjusted to detect the virus in the milk. Thirty to forty-one percentage of the udders of 101 cows with bacterial mastitis (Escherichia coli, Streptococcus uberis or Staphylococcus aureus) gave positive results, whereas less than 6% of the milk samples were positive for BoHV-4 from 118 animals with healthy udders. The mastitis status of these 118 healthy cows was followed throughout the milking period; 4.2% had clinical, and 25.42% had subclinical mastitis. By the end of the milking period, more than 90% of the cows shed the virus in their milk, regardless of the bacterial status of the udder. No correlation was found between the virus shed, the somatic cell count, and the bacterial status of the udder. Viral DNA was detected in the wall of the milk duct. These results demonstrate that BoHV-4 neither causes mastitis directly nor plays a role in the initiation of the process, but later, when bacterial infection of the udder occurs, the reactivated virus replicates in the immune cells of the udder and/or in the epithelial cells of the...Continue Reading

References

Nov 1, 1992·Veterinary Microbiology·E ThiryP P Pastoret
Jan 1, 1994·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J P Quinn
Jun 1, 1993·Molecular and Cellular Probes·S Belák, A Ballagi-Pordány
Sep 20, 2000·The Veterinary Record·G J WellenbergJ T Van Oirschot
Apr 12, 2001·The Journal of General Virology·G Donofrio, V L van Santen
Apr 21, 2001·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·G W Bornkamm, W Hammerschmidt
Aug 3, 2001·Journal of Virological Methods·G J WellenbergJ T Van Oirschot
Nov 29, 2001·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·K FrazierC A Baldwin
Jul 18, 2002·Veterinary Microbiology·G J WellenbergJ T Van Oirschot

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Citations

Mar 1, 2011·Microbial Pathogenesis·László EgyedOttó Szenci
Sep 5, 2006·Microbial Pathogenesis·Zoltán DeimLászló Egyed
Sep 4, 2013·Transboundary and Emerging Diseases·S Chastant-Maillard
Sep 19, 2009·Journal of Dairy Science·H W BarkemaR N Zadoks
Jan 21, 2009·Journal of Physics. Condensed Matter : an Institute of Physics Journal·Daniel Jost, Ralf Everaers
Jul 6, 2010·Animal Science Journal = Nihon Chikusan Gakkaihō·Sibel Gür, Nurhan Doğan
Sep 15, 2018·Journal of Wildlife Diseases·Claudio VerdugoCarlos Hernandez

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