Role of cardiac multidetector computed tomography beyond coronary angiography

Circulation Journal : Official Journal of the Japanese Circulation Society
Akira Sato, Kazutaka Aonuma

Abstract

Cardiac multidetector computed tomography (MDCT) has become a useful noninvasive modality for anatomical imaging of coronary artery disease (CAD). Currently, the main clinical advantage of coronary computed tomography angiography (CCTA) appears to be related to its high negative predictive value at low or intermediate pretest probability for CAD. With the development of technical aspects of MDCT, clinical practice and research are increasingly shifting toward defining the clinical implication of plaque morphology, myocardial perfusion, and patient outcomes. The presence of positive vessel remodeling, low-attenuation plaques, napkin-ring sign, or spotty calcification on CCTA could be useful information on high-risk vulnerable plaques. The napkin-ring sign, especially, showed higher accuracy for the detection of thin-cap fibroatheroma. Recently, it was reported that cardiac 3D single-photon emission tomography/CT fusion imaging, noninvasive fractional flow reserve computed from CT, and integrated CCTA and CT myocardial perfusion were associated with improved diagnostic accuracy for the detection of hemodynamically significant CAD. Furthermore, several randomized, large clinical trials have evaluated the clinical value of CCTA for...Continue Reading

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Citations

Oct 27, 2015·Circulation Journal : Official Journal of the Japanese Circulation Society·Koki NakanishiKenei Shimada
Jan 19, 2016·La Revue de médecine interne·L Di MarcoM Ohana
Mar 30, 2016·Circulation Journal : Official Journal of the Japanese Circulation Society·Teruhito KidoSachio Kuribayashi
Oct 28, 2016·Circulation Journal : Official Journal of the Japanese Circulation Society·Hideaki YukiYasuyuki Yamashita
Feb 26, 2019·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Sung Min KoSung Ho Hwang
Feb 15, 2017·Cardiovascular Endocrinology·Yanglu Zhao

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