Role of computed tomography before lumbar puncture: a survey of clinical practice

Postgraduate Medical Journal
P R Greig, D Goroszeniuk

Abstract

It is becoming increasingly common to request computed tomography (CT) to rule out space occupying lesions before lumbar puncture (LP), even in patients with no clinical signs. Imaging trends within a busy district general hospital in Oxfordshire, UK were analysed with results used to clarify when imaging should be considered mandatory. A retrospective six month sample was obtained comprising all adults considered for LP. Observed frequencies of abnormal examination findings compared with abnormal investigations were used to determine sensitivity, specificity, positive predictive, and negative predictive values to assess the validity of using a normal clinical examination as a basis for excluding CT. 64 patients were considered for LP. In total, 58 patients underwent LP, with a single patient receiving two. After an abnormal CT scan, six patients did not undergo a planned LP. In all six of these cases subarachnoid haemorrhage was detected, and in all cases this was considered a probable diagnosis. In no case was an LP precluded by an unsuspected space occupying lesion. Neurological examination showed a sensitivity of 0.72 (0.52 to 0.93), specificity 0.78 (0.64 to 0.91), positive predictive value 0.61 (0.41 to 0.83), and negativ...Continue Reading

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Jun 27, 2013·Current Treatment Options in Neurology·Diedre Hofinger, Larry E Davis
Jul 29, 2009·Clinical Medicine : Journal of the Royal College of Physicians of London·Rhys H Thomas, Philip E M Smith
Nov 14, 2013·Emergency Medicine International·Kelli N O'LaughlinWilliam R Mower
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Apr 22, 2008·Internal Medicine Journal·J WilliamsT Umapathi

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